Advisory Prerequisites: Introductory classes in microbiology and biochemistry - contact instructor if in doubt
Undergraduates are allowed to enroll in this course.
Description: The influence of microorganisms on human-health is significant and control strategies often rely on the use of physical (heat, UV, etc) and chemical (antimicrobial, antibiofilm, etc) technologies. This course will focus on such endeavors with particular focus on broad acting antimicrobials (less emphasis on antibiotics) and new/remerging microbial control technologies.
Course Goals: This course has three main goals: (1) Familiarize students with first-line methods to control populations of microorganisms. These methods will be in contrast to the use of antibiotics. First-line methods that will be described include physical and chemical treatment strategies such as heat and filter sterilization, disinfectants, mechanisms and use of broad acting biocides, as well as new emerging technologies such as quorum sensing inhibitors (2) Introduce the concept of multi-species biofilm communities, their recalcitrance and ability to enhance selection of antimicrobial resistance. (3) Discuss strategies that are or could be adopted to enhance microbial control strategies in the domestic, public and medical setting.
Competencies: 2. D. Human Physiology and Pathology Knowledge 1.The biochemical and cellular basis for normal and pathological functioning 2.Interaction among anatomical systems and organs in health and disease. 3.The most important chronic, infectious, and degenerative diseases of humans in terms of the public's health 4.Pathobiology of major diseases integrated with the principles of epidemiology. 5.The impact of host characteristics (e.g., immune response, nutrition, presence of other diseases or infections) on disease outcomes