Courses Details

PUBHLTH413: Vaccines in Public Health

  • Undergraduate level
  • Winter term(s)
  • 3 Credit Hour(s)
  • Instructor(s): Yang, Zhenhua
  • Prerequisites: PUBHLTH370 or EPID512
  • Advisory Prerequisites: Introductory Infectious Disease Courses
  • Description: This course introduces essential vaccinology, covering pre-clinical vaccine development, clinical trials, new vaccine licensing, immunization program design and evaluation. It also introduces population transmission dynamics concepts, and the impact of pathogen and human population diversity on vaccination. Recent advancements in major types of non-infectious vaccines will also be discussed.
  • Course Goals:
    1. To introduces the students to the history and evolution of vaccinology, and the principles and methods of epidemiology, statistics, microbiology, immunology, and genetics used in vaccine development and immunization program design.
    2. To introduce the students to the general procedures for new vaccine development and licensure, including the different phases of clinical trials of new vaccines.
    3. To introduces the students to the concepts of population transmission dynamics, and the impact of pathogen and human population genetic diversity on vaccine development.
    4. To expose the students to the new frontiers of vaccines - development of vaccines for major types of non-infectious diseases.
  • Competencies:

    Although there is no official competencies that have been established for the new public health undergraduate program, this course addresses, partially or substantially, a number of BS in Public Health Sciences Requirements, which include:

    • Gain an understanding of the natural history of infectious and chronic diseases, their environmental and biological origins, their distributions among populations, and strategies for their prevention and management.
    • Examine and explore multiple aspects of infectious and chronic diseases, including socio-economic, behavioral, biological, environmental, and structural factors that contribute to their origin and distribution among populations.
    • Understand the basic biology, transmission, and natural history of important human infectious and chronic diseases.
    • Examine methodologies that are used in public health to study the underlying causes and impact of various aspects of infectious and chronic diseases, including surveillance, epidemiological investigations, and mathematical modeling.
    • Explore multi-tiered public health strategies for the prevention, treatment, and potential eradication of infectious and chronic diseases.
  • Learning Objectives:
    1. To gain an understanding of how new knowledge generated from epidemiological studies from different populations, basic biomedical science research, and health policy assessment, along with the development of new technology, can jointly inform and impact the development of new vaccines for the prevention of different types of diseases, including both infectious and non-infectious diseases.
    2. to be familiar with the essential steps involved in developing a new vaccine.
    3. to understand important factors that affect the efficacy, effectiveness, and the public acceptance of vaccination.
  • This course is cross-listed with EPID 513 in the Epidemiology Department department.
  • Syllabus for PUBHLTH413