Courses Taught by Carl F Marrs

EPID460 Introduction to Bacterial Pathogenesis

  • Graduate level
  • Winter term(s)
  • 3 Credit Hour(s)
  • Instructor(s): Marrs, Carl F
  • Prerequisites: Introductory Microbiology and Genetics or Perm. Instr.
  • Description: This course covers the basics of the biochemistry, molecular biology, and genetics of chemotaxis and flagella, pili and adhesins, extracellular proteases, bacterial toxins, invasion and intracellular growth, phase and antigenic variation, gene transfer, LPS, iron, M-proteins, capsules, chemotherapy, antibiotic resistance and global regulation of virulence elements.
  • Syllabus for EPID460

EPID511 Introduction to Public Health Genetics

  • Graduate level
  • Fall term(s)
  • 3 Credit Hour(s)
  • Instructor(s): Marrs, Carl F
  • Last offered Fall 2015
  • Prerequisites: Grad status or perm instructor
  • Description: This course is designed for those interested in a basic understanding of human genetics who have had only a very limited exposure to biologic sciences. This course will cover the basics of genetics at both the molecular and population level. In addition to the basic science, some ethical, legal, and social implications of genetics research will be examined. Examples relevant to public health will be emphasized.
  • This course is cross-listed with in the PUBHLTH 311 department.
  • Syllabus for EPID511

EPID560 Mechanisms of Bacterial Pathogenesis

  • Graduate level
  • Fall term(s)
  • 3 Credit Hour(s)
  • Instructor(s): Marrs, Carl F
  • Offered every year
  • Last offered Fall 2015
  • Prerequisites: Grad Status and Intro Microbiology and Biochemistry or Perm. Instr.
  • Description: Microbial structures and their relation to basic mechanisms of bacterial pathogenesis; structure, function, and genetics of bacterial toxins; and host resistance and immunity. Discussions of pathogenic organisms of major public health importance, diseases caused, and their epidemiology.
  • Syllabus for EPID560

PUBHLTH311 Introduction to Public Health Genetics

  • Undergraduate level
  • Fall term(s)
  • 3 Credit Hour(s)
  • Instructor(s): Marrs, Carl F
  • Prerequisites: None
  • Description: Course designed for those with limited exposure to biology who are interested in human genetics. Will include basics of genetics at both the molecular and population level, plus some ethical, legal, and social implications of genetics research will be examined. Examples relevant to public health will be emphasized.
  • Course Goals: The goal of this course is to teach the basics of genetics so that students who successfully complete the course will be prepared to take any additional courses that have introductory genetics as a prerequisite.
  • Competencies: Course Learning Outcomes: 1) Describe how the concepts of Mendel are relevant to human genetic diseases. 2) Understand the fundamental mechanisms of how genetic information is transmitted from one generation to the next. 3) Understand how the genetic information is translated into the materials needed to create the body and allow it to function. 4) Understand the different types of mutations that can occur and their consequences. 5) Analyze how variations in populations affect our abilities to determine the genetic elements involved in disease. 6) Describe the role genetic changes play in cancer development. 7) Understand the role of genetic screening and testing in public health and medicine. 8) Discuss some of the ethical, legal and social issues associated with human genetics.
  • Syllabus for PUBHLTH311

PUBHLTH460 Introduction to Bacterial Pathogenesis

  • Undergraduate level
  • Winter term(s)
  • 3 Credit Hour(s)
  • Instructor(s): Marrs, Carl F
  • Prerequisites: Pubhlth 370 or Bio 207, AND Pubhlth 311 or Bio 305
  • Description: Microbial structures and their relation to basic mechanisms of bacterial pathogenesis; structure, function, and genetics of bacterial toxins; and host resistance and immunity. Discussions of pathogenic organisms of major public health importance, diseases caused, and their epidemiology.
  • Course Goals: The goals of this course are to have the students gain a basic understanding of the kinds of virulence factors used by pathogenic bacteria to cause disease, how we discover and study those traits, and how we can make use of this knowledge for treatment and prevention of bacterial diseases.
  • Competencies: 1. Understand the role played by bacteria in human health and disease. 2. Understand how genetic transfer mechanisms can lead to bacteria with increased virulence and antibiotic resistance. 3. Understand how bacterial toxins and other virulence factors help bacteria cause disease. 4. Understand public health approaches to preventing bacterial diseases. 5. Understand how antibiotics kill bacteria and how bacteria become resistant to them.
  • Learning Objectives: 1. Understand the role played by bacteria in human health and disease. 2. Understand how genetic transfer mechanisms can lead to bacteria with increased virulence and antibiotic resistance. 3. Understand how bacterial toxins and other virulence factors help bacteria cause disease. 4. Understand public health approaches to preventing bacterial diseases. 5. Understand how antibiotics kill bacteria and how bacteria become resistant to them.
  • This course is cross-listed with Epid 460 in the Epidemiology, SPH department.