Dr. Carl F. Marrs is an Associate Professor of Epidemiology and has been part of the Hospital and Molecular Epidemiology faculty within the department since 1985. In addition to teaching and research, Dr. Marrs has been head of admissions for MPH students in the Epidemiology Department since 1992. Dr. Marrs was an interim director of the Public Health Genetics Interdepartmental Concentration, and is currently a faculty member of the steering committee for the Public Health Genetics Certificate program. Dr. Marrs is also involved in undergraduate education. He serves as a member of the SPH Committee on Undergraduate Education, and advises students in the Undergraduate Concentration in Microbiology, as well as teaching the undergraduate level course, Epid 460. At a university wide level, Dr. Marrs has served at various capacities (including a stint as chair) on the University of Michigan Institutional Biosafety Committee, and he is currently Associate Chair of that committee. Dr. Marrs' primary research expertise is in bacterial pathogenesis and genetics. He is involved in a wide variety of molecular epidemiologic research collaborations as part of the Center for Molecular and Clinical Epidemiology of Infectious Diseases (MAC-Epid). These include, but are not limited to, studies on Haemophilus influenzae in both otitis media and chronic obstructive pulmonary disease (COPD); studies on Escherichia coli in both urinary tract infections and diarrheal disease; studies on Streptococcus agalactiae; Streptococcus mutans; Acinetobacter; Mycobacterium tuberculosis; and the microbiota of the oral and vaginal tracts.
- EPID460: Introduction to Bacterial Pathogenesis Syllabus (PDF)
- EPID511: Introduction to Public Health Genetics Syllabus (PDF)
- EPID560: Mechanisms of Bacterial Pathogenesis Syllabus (PDF)
- PUBHLTH311: Introduction To Public Health Genetics Syllabus (PDF)
- PUBHLTH460: introduction to bacterial pathogenesis
- PhD, Molecular Biology, University of Wisconsin, 1982
- B.S., Chemistry, University of Washington, 1975
Research Interests & Projects
- Molecular epidemiology of Group B Streptococcus and Escherichia coli; Virulence related genetic variation of Mycobacterium tuberculosis strains; Haemophilus influenzae genes associated with acute otitis media and COPD; Transmission dynamics and antibiotic resistance in Escherichia coli; Antibiotic resistance gene resistance transfer in biofilms; Public health genetics; Molecular epidemiology of oral and vaginal bacteria.
- Yang, Z., M. Rosenthal, N.A. Rosenberg, S. Talarico, L. Zhang, C. Marrs, V.Ø. Thomsen, T. Lillebaek, and A.B. Andersen. 2011. How dormant is Mycobacterium tuberculosis during latency? A study integrating genomics and molecular epidemiology. Infection, Genetics and Evolution 11:1164-1167.
- Spicknall, I.H, B. Foxman, C.F. Marrs, J.N.S. Eisenberg. 2013. A modeling framework for the evolution and spread of antibiotic resistance: Literature review and model categorization. American J. Epidemiol. 178:508-520.
- LaCross, N.C., C.F. Marrs, and J.R. Gilsdorf. 2013. Population structure in nontypeable Haemophilus influenzae. Infection Genetics Evolution 14:125-136.
- Foxman, B., U. Srinivasan, A. Wen, L. Zhang, C.F. Marrs, D. Goldberg, R. Weyant, D. McNeil, R. Crout, and M. Marazita. 2014. Exploring the effect of dentition, dental decay and familiality on oral health using metabolomics. Infection, Genetics and Evolution 22:201-207.
- LaCross, N.C., C.F. Marrs, and J.R. Gilsdorf. 2014. Otitis media associated polymorphisms in the hemin receptor HemR of nontypeable Haemophilus influenzae. Infection, Genetics & Evolution 26:47-57.
- Dang, T.N.D., Z. Britt, U. Srinivasan, S. Ponnaluri, C.F. Marrs, L. Zhang, M. Ki, and B. Foxman. 2014. Efflux-mediated resistance identified among norfloxacin resistant clinical strains of group B Streptococcus from South Korea. Epidemiology and Health 36:e2014022.
- Foxman, B., A. Wen, U. Srinivasan, D. Goldberg, C.F. Marrs, J. Owen, D. Wing, and D. Misra. 2014. Mycoplasma, bacterial vaginosis associated bacteria BVAB3, race and risk of preterm birth in a high risk cohort. American Journal of Obstetrics and Gynecology 210: 226.e1-7.
- Hariadi, N., L. Zhang, M. Patel, S. Sandstedt, G. Davis, C. Marrs, and J. Gilsdorf. 2015. Comparative profile of heme acquisition genes in disease-causing and colonizing nontypeable Haemophilus influenzae and Haemophilus haemolyticus. J. Clin. Microbiol. 53:7 2132-2137.
- Zhang, L., K. Levy, G. Trueba, W. Cevallos, J. Trostle, B. Foxman, C.F. Marrs, J.N.S. Eisenberg. 2015. The effects of selection pressure and genetic association on the relationship between antibiotic resistance and virulence in Escherichia coli. Antimicrobial Agents and Chemotherapy 59:6733-6740.
- Bhavnani, D., R. de los Ángeles Bayas, V.K. Lopez, L. Zhang, G. Trueba, B. Foxman, C. Marrs, W. Cevallos, J.N.S. Eisenberg. 2016. Distribution of enteroinvasive and enterotoxigenic Escherichia coli across space and time in Northwestern Ecuador. American Journal of Tropical Medicine & Hygiene 94:276-284.
- American Association for the Advancement of Science