Cathie Spino, Sc.D.
- Research Professor of Biostatistics
- Director of Statistical Analysis of Biomedical and Educational Research (SABER)
- M2079 SPH II
- 1415 Washington Heights
- Ann Arbor, Michigan 48109-2029
Cathie Spino is a Research Professor and Director of Statistical Analysis of Biomedical and Educational Research (SABER) in the Department of Biostatistics. As the Director of SABER, she collaborates with investigators on the design and analysis of multi-center clinical trials or other research projects, and provides oversight of the infrastructure necessary to conduct these studies, including project management, clinical monitoring, database development and web-based data entry. She joined the department in September 2007, after spending ten years in the pharmaceutical industry as a statistician and statistical manager. She began her career in academia as an assistant professor in the Department of Biostatistics at the Harvard School of Public Health, after receiving her D.Sc. degree there in 1989. She was a statistician in the Statistical and Data Analysis Center (SDAC) of the AIDS Clinical Trials Group (ACTG), and eventually served as the Assistant Director of SDAC for the Pediatric ACTG. Her research interests include clinical trials methodology, particularly adaptive designs, and women's and children's health.
- Sc.D., Biostatistics, Harvard University School of Public Health, 1989
- M.S., Biostatistics, Harvard University School of Public Health, 1985
- B.S., Mathematics and Statistics, Miami University, 1983
- Mack CL, Spino C, Alonso EM, Bezerra JA, Moore J, Goodhue C, Ng VL, Karpen SJ, Venkat V, Loomes KM, Wang K, Sherker AH, Magee JC, Sokol RJ (2019). A Phase I/IIa Trial of Intravenous Immunoglobulin Following Portoenterostomy in Biliary AtresiaJournal of pediatric gastroenterology and nutrition
- Loomes KM, Spino C, Goodrich NP, Hangartner TN, Marker AE, Heubi JE, Kamath BM, Shneider BL, Rosenthal P, Hertel PM, Karpen, Molleston, Murray, Schwarz, Squires, Teckman, Turmelle SJ, Alonso EM, Sherker AH, Magee JC, Sokol RJ, Childhood Liver Disease Research Network (2019) Bone Density in Children With Chronic Liver Disease Correlates With Growth and CholestasisHepatology 69(1): 245-257
- Shneider BL, Spino C, Kamath BM, Magee JC, Bass LM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Murray KF, Loomes KM, Rosenthal P, Karpen SJ, Leung DH, Guthery SL,Thomas D, Sherker AH, Sokol RJ, Childhood Liver Disease Research Network (2018). Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille SyndromeHepatology Communications 2(10): 1184-1198.
- Flaherty K, De Andrade J, Lancaster L, Limb S, Lindell K, Nathan S, Raghu G, Spino C, Stauffer J, Wolters P, Cosgrove G (2018). Baseline characteristics of 1461 participants in the Pulmonary Fibrosis Foundation Patient RegistryEuropean Respiratory Journal 52: PA2199
- Gao C, Sun H, Wang T, Tang M, Bohnen NI, Müller MLTM, Herman T, Giladi N, Kalinin A, Spino C, Dauer W, Hausdorff JM, Dinov ID (2018). Model-based and model-free machine learning techniques for diagnostic prediction and classification of clinical outcomes in Parkinson’s diseaseScientific reports 8(1): 7129.
Kotagal V, Spino C, Bohnen NI, Koeppe R, Albin RL (2018) Serotonin, β‐amyloid, and cognition in Parkinson diseaseAnnals of Neurology 83(5): 994-1002
- Bezerra JA, Spino C, Magee JC, Shneider BL, Rosenthal P, Wang KS, Erlichman J, Haber B, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston JP, Murray KF, Romero R, Schwarz KB, Shepherd R, Suchy FJ, Turmelle YP, Whitington PF, Moore J, Sherker AH, Robuck PR, Sokol RJ, for the Childhood Liver Disease Research and Education Network (ChiLDREN). (2014). Effect of High Dose Corticosteroids following Hepatoportoenterostomy on Bile Drainage in Infants with Biliary Atresia: The START Randomized Clinical Trial. Journal of the America Medical Association, 311(17):1750-1759. [PMC4303045]
- Wei JT, Nygaard I, Richter HE, Nager CW, Barber MD, Kenton K, Amundsen CL, Schaffer J, Meikle SF, Spino C for the Pelvic Floor Disorders Network. (2012). A Midurethral Sling to Reduce Incontinence after Vaginal Prolapse.New England Journal of Medicine, 366:2358-2367. [PMC3433843]
- American Statistical Association