Jeremy M G Taylor, Ph.D.
- Professor, Department of Biostatistics
- Pharmacia Research Professor, Department of Biostatistics
- Professor, Department of Radiation Oncology
- Professor, Department of Computational Medicine and Bioinformatics
- Associate Director for Biostatistics, Comprehensive Cancer Center
- Professor, Department of Biostatistics
- M4509 SPH II
- 1415 Washington Heights
- Ann Arbor, Michigan 48109-2029
- B.A., Honours Mathematics, Cambridge University, 1978
- Dip. Stat., Statistics, Cambridge University, 1979
- Ph.D., Statistics, University of California, Berkeley, 1983
Research Interests & Projects
My interests are the theory and application of statistics to biomedical problems. I believe that data-driven, robust, flexible statistical methods should be used, incorporating scientific knowledge from the substantive area of investigation. A good statistician has to be heavily involved in the underlying science of the data he/she is investigating.
My research has focused on the application of statistics to cancer and AIDS, especially to radiation oncology. The specific areas are modelling, survival analysis and longitudinal data. This has led to developing methods involving the use of mixture models, stochastic processes and multiple imputation.
My theoretical statistical interests are in Box-Cox power transformations, robust methods, nonparametrics and smoothing techniques.
My previous research in radiation oncology has focussed on the effect of fraction size, total dose, time and volume on the biological response to radiation. I have studied the response of both tumours and normal tissues to radiation.
My work related to cancer has focused on modelling and evaluating biomarkers, particularly PSA in prostate cancer. More recent applied work has been concerned with methods for combining multiple biomarkers, methods for analysing data from gene expression arrays, evaluation of surrogate and auxiliary variables and design of phase I trials in oncology.
- Foster, JC, Taylor, JMG, and Ruberg, SJ: “Subgroup Identification from Randomized Clinical Trial Data.” Stats Med, 30(24): 2867-80, 2011, PMC3880775.
- Park YS, Taylor JMG, Kalbfleisch J: "Pointwise Nonparametric Maximum Likelihood Estimator of Stochastically Ordered Survivor Functions". Biometrika, 99(2): 327-343, 2012, PMC3635706, (Snedecor Award Paper, 2013).
- Boonstra PS, Mukherjee B, Taylor JMG: “Bayesian shrinkage methods for partially observed data with many predictors.” Annals of Applied Statistics, 7(4):2272-92, 2013, PMC3891514.
- Taylor JMG, Park Y, Ankerst DP, Proust-Lima C, Williams S, Kestin L, Bae K, Pickles T, Sandler H: “Real-Time Individual Predictions of Prostate Cancer Recurrence Using Joint Models.” Biometrics, 69(1): 206–213, 2013, PMC3622120.
- McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MYC, Kim KY, Tricoli JV, Taylor JMG, Shuman DJ, Simon RM, Doroshow JH, Conley BA: “Criteria for the Use of Omics-Based Predictors In Clinical Trials.” Nature, 502(7471):317-20, 2013, PMC4180668.
- Conlon ASC, Taylor JMG, Sargent DJ: “Multi-State Models for Colon Cancer Recurrence and Death with a Cured Fraction.” Stat Med, 33(10):1750-66, 2014, PMC3999912.
- Boonstra PS, Shen J, Taylor JMG, Braun TM, Griffith KA, Daignault SD, Kalemkerian GP, Lawrence TS. Schipper MJ: “A Statistical Evaluation of Dose Expansion Cohorts in Phase I Clinical Trials”. JNCI, 107(3). doi: 10.1093/jnci/dju429. 2015, PMC4565529.
- Boonstra PS, Mukherjee B and Taylor JMG: “Data-Adaptive Shrinkage via the Hyperpenalized EM Algorithm”. Statistics in Biosciences,7(2):417-431, 2015 PMC4728141.
- Rizopoulos D, Taylor JMG, van Rosmalen J, Steyerberg EW, Takkenberg JJM: “Personalized Screening Intervals for Biomarkers Using Joint Models for Longitudinal and Survival Data.” Biostatistics, 17(1):149-64, 2015, PMC46790704.
- Beesley L, Bartlett J, Wolf G, Taylor JMG: “Multiple Imputation of Missing Covariates for the Cox Proportional Hazards Cure Model.” Stat Med, 35(26): 4701-4717, 2016 PMC5053880
- Rice JD, Taylor JMG: “Locally Weighted Score Estimation for Quantile Classification in Binary Regression Models.” Stat Biosci, 8(2):333-350, 2016, PMC5173294.
- Prince V, Bellile EL, Sun Y, Wolf GT, Hoban CW, Shuman AG, Taylor JMG: “Individualized Risk Prediction of Outcomes for Oral Cavity Cancer Patients” Oral Oncology, (63):66-73, 2016, PMC5193389.
- Conlon ASC, Taylor JMG, Elliott MR: “Surrogacy Assessment Using Principal Stratification and a Gaussian Copula Model.” Stat Methods Med Res, 26(1):88-107, 2017, PMC4272338
- Shen J, Wang L, Taylor JMG: “Estimation of the Optimal Regime in Treatment of Prostate Cancer Recurrence from Observational Data Using Flexible Weighting Models.” Biometrics, 73(2):635-645, 2017, PMC5466876.
- Suresh K, Taylor JMG, Spratt DE, Daignault S, Tsodikov A: “Comparison of joint modeling and landmarking for dynamic prediction under an illness-death model.” Biom J, 59(6):1277-1300, 2017, PMID: 28508545.
- Cheng W, Taylor JMG, Mukherjee B, Vokonas P, Park SK: “Improving estimation in linear regression incorporating external information from an established reduced model.” Stat Med, 37(9):1515-1530, 2018, PMC5889759.
- Hoban CW, Beesley LJ, Bellile EL, Sun Y, Spector ME, Wolf GT, Taylor JMG Shuman A: “Individualized Outcome Prognostication for Patients with Laryngeal Cancer.” Cancer, 124(4):706-716, 2018, PMC5800991.
- Estes J, Mukherjee B, Taylor JMG: “Empirical Bayes Estimation and Prediction Using Summary-Level Information From External Big Data Sources Adjusting for Violations of Transportability.” Stat Biosci, pp 1-19, 2018
- Royal Statistical Society
- American Statistical Association
- International Biometrics Society
- Institute of Mathematical Statistics
- International Statistical Institute
- Radiation Research Society