Faculty Profile

Matthew Zawistowski

Matthew Zawistowski, PhD

  • Clinical Associate Professor, Biostatistics

Matthew Zawistowski is a Clinical Associate Professor of Biostatistics. Matt completed his dissertation and postdoc in Biostatistics at the University of Michigan, focusing on problems in statistical and population genetics. In particular, he develops statistical methods for analyzing genetic variants identified in large-scale genome sequencing studies to better understand human populations and disease. Following his postdoc, Matt worked briefly at the Ann Arbor VA where he gained valuable experience working with Electronic Health Records. He is currently part of the Michigan Genomics Initiative (MGI), which combines his interests in genomics and phenotyping through Electronic Health Records. Throughout his career, Matt has been passionate about teaching math and statistics. He was awarded the 2022 SPH Excellence in Teaching award.

  • PhD, Biostatistics, University of Michigan, 2011
  • MS, Biostatistics, University of Michigan, 2007
  • MS, Mathematics, Lehigh University, 2005
  • BS, Mathematics, Saint Joseph's University, 2003

Research Interests:
Statistical and Population Genetics, Electronic Health Records, Risk Prediction, Precision Medicine, Statistics Education

Vanderwerff B, Pasternak AL, Fritsche LG, Bertucci-Richter E, Patil S, Boehnke M, Zhou X, Zöllner S, Hertz DL, Zawistowski M. Expanding biobank pharmacogenomics through machine learning calls of structural variation. Genetics. 2025 Jul 9;230(3):iyaf088. doi: 10.1093/genetics/iyaf088. PMID: 40344017.
 
Belbellaj W, Lona-Durazo F, Bodano C, Busseuil D, Cyr MC, Fiorillo E, Mulas A, Provost S, Steri M, Tanaka T, Vanderwerff B, Wang J, Byrne RP, Cucca F, Dubé MP, Ferrucci L, McLaughlin RL, Tardif JC Zawistowski M, Gagliano Taliun SA. The role of genetically predicted serum iron levels on neurodegenerative and cardiovascular traits. Sci Rep. 2024 Oct 19;14(1):24588. doi: 10.1038/s41598-024-76245-9. PMID: 39427026; PMCID: PMC11490554.
 
Mosley JD, Shelley JP, Dickson AL, Zanussi J, Daniel LL, Zheng NS, Bastarache L, Wei WQ, Shi M, Jarvik GP, Rosenthal EA, Khan A, Sherafati A, Kullo IJ, Walunas TL, Glessner J, Hakonarson H, Cox NJ, Roden DM, Frangakis SG, Vanderwerff B, Stein CM, Van Driest SL, Borinstein SC, Shu XO, Zawistowski M, Chung CP, Kawai VK. Clinical associations with a polygenic predisposition to benign lower white blood cell counts. Nat Commun. 2024 Apr 22;15(1):3384. doi: 10.1038/s41467-024-47804-5. PMID: 38649760; PMCID: PMC11035609
 
Bastarache L, Delozier S, Pandit A, He J, Lewis A, Annis AC, LeFaive J, Denny JC, Carroll RJ, Altman RB, Hughey JJ, Zawistowski M, Peterson JF. The phenotype-genotype reference map: Improving biobank data science through replication. Am J Hum Genet. 2023 Sep 7;110(9):1522-1533. doi: 10.1016/j.ajhg.2023.07.012. Epub 2023 Aug 21. PMID: 37607538; PMCID: PMC10502848.
 
Reiner A, Bakulski KM, Fisher JD, Dou JF, Schneper L, Mitchell C, Notterman DA, Zawistowski M *, Ware EB*. Sex-specific DNA methylation in saliva from the multi-ethnic Fragile Families and Child Wellbeing Study. Epigenetics 2023. PMID: 37300819; PMCID: PMC10259311. (* co-senior authors) 
 
Zawistowski M, Fritsche LG, Pandit A, Vanderwerff B, Patil S, Schmidt EM, VandeHaar P, Willer CJ, Brummett CM, Kheterpal S, Zhou X, Boehnke M, Abecasis GR, Zöllner S. The Michigan Genomics Initiative: A biobank linking genotypes and electronic clinical records in Michigan Medicine patients. Cell Genom. 2023 Jan 31;3(2):100257. doi: 10.1016/j.xgen.2023.100257. PMID: 36819667; PMCID: PMC9932985.

M4025 SPH II
1415 Washington Heights
Ann Arbor, MI 48103

Phone: (734) 615-9618
Email: [email protected] 

https://sph.umich.edu/bdsi/index.html

Areas of Expertise: Biostatistics