Publications

Publications are one measure of the quality of a study and its data. SABER biostatisticians have led analytic efforts for studies that have been published in top-tier medical journals such as The New England Journal of Medicine, The Journal of the American Medical Association, and The Lancet.

Stent Vs. Indomethacin For Preventing Post-ERCP Pancreatitis (SVI)

  1. Elmunzer BJ, Serrano J, Chak A, Edmundowicz SA, Papachristou GI, Scheiman JM, Singh VK, Varadurajulu S, Vargo JJ, Willingham FF. Rectal indomethacin alone versus indomethacin and prophylactic pancreatic stent placement for preventing pancreatitis after ERCP: study protocol for a randomized controlled trial. Trials. 2016;17(1):120.

A Randomized, Double-Blinded, Placebo-Controlled Trial Of Corticosteroid Therapy Following Portoenterostomy In Infants With Biliary Atresia (START)

  1. Venkat VL, Shneider BL, Magee JC, Turmelle Y, Arnon R, Bezerra JA, Hertel PM, Karpen SJ, Kerkar N, Loomes KM. Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia. Journal of pediatric gastroenterology and nutrition. 2014;59(6):702.
  2. Bezerra JA, Spino C, Magee JC, Shneider BL, Rosenthal P, Wang KS, Erlichman J, Haber B, Hertel PM, Karpen SJ. Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial. Jama. 2014;311(17):1750-9.
  3. Shneider BL, Magee JC, Bezerra JA, Haber B, Karpen SJ, Raghunathan T, Rosenthal P, Schwarz K, Suchy FJ, Kerkar N. Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia. Pediatrics. 2012;130(3):e607-e14.

Preventing Urinary Tract Infection Post Surgery – A Double-Blind, Placebo-Controlled Study Of The Effect Of Cranberry Capsules (PUPS)

  1. Foxman B, Cronenwett AE, Spino C, Berger MB, Morgan DM. Cranberry juice capsules and urinary tract infection after surgery: results of a randomized trial. American journal of obstetrics and gynecology. 2015;213(2):194
  2. Marschall J, Piccirillo ML, Foxman B, Zhang L, Warren DK, Henderson JP. Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital. BMC infectious diseases. 2013;13(1):213.
  3. Marschall J, Zhang L, Foxman B, Warren DK, Henderson JP. Both host and pathogen factors predispose to Escherichia coli urinary-source bacteremia in hospitalized patients. Clinical infectious diseases. 2012;54(12):1692-8.

Randomized Evaluation of VAD InterVEntion before Inotropic Therapy (REVIVE-IT) Pilot Trial (REVIVE-IT)

  1. Baldwin JT, Mann DL. NHLBI's program for VAD therapy for moderately advanced heart failure: the REVIVE-IT pilot trial. Journal of cardiac failure. 2010;16(11):855-8.
  2. Pagani FD, Aaronson KD, Kormos R, Mann DL, Spino C, Jeffries N, Taddei-Peters WC, Mancini DM, McNamara DM, Grady KL. The NHLBI REVIVE-IT study: Understanding its discontinuation in the context of current left ventricular assist device therapy. Elsevier; 2016.

Reducing Particulate Matter-Associated Cardiovascular Health Effects for Seniors

  1. Maestas MM, Brook RD, Ziemba RA, Li F, Crane RC, Klaver ZM, Bard RL, Spino CA, Adar SD, Morishita M. Reduction of personal PM2.5 exposure via indoor air filtration systems in Detroit: an intervention study. Journal of Exposure Science and Environmental Epidemiology (accepted) (2018).

Pessary vs behavioral therapy - ATLAS (PFDN-ATLAS)

  1. Borello-France D, Burgio KL, Goode PS, Ye W, Weidner AC, Lukacz ES, Jelovsek J-E, Bradley CS, Schaffer J, Hsu Y. Adherence to behavioral interventions for stress incontinence: rates, barriers, and predictors. Physical therapy. 2013;93(6):757.
  2. Kenton K, Barber M, Wang L, Meikle S, Hsu Y, Rahn D, Whitcomb E, Amundsen C, Bradley C, Zyczynski H. Pelvic floor symptoms improve similarly after pessary and behavioral treatment for stress incontinence. Female pelvic medicine & reconstructive surgery. 2012;18(2):118.
  3. Schaffer J, Nager CW, Xiang F, Borello-France D, Bradley CS, Wu JM, Mueller E, Norton P, Paraiso MFR, Zyczynski H. Predictors of success and satisfaction of nonsurgical therapy for stress urinary incontinence. Obstetrics and gynecology. 2012;120(1):91.

CARE: Colpopexy And urinary Reduction Efforts (PFDN-CARE)

  1. Jelovsek JE, Chagin K, Brubaker L, Rogers RG, Richter HE, Arya L, Barber MD, Shepherd JP, Nolen TL, Norton P. A model for predicting the risk of de novo stress urinary incontinence in women undergoing pelvic organ prolapse surgery. Obstetrics and gynecology. 2014;123(2 0 1):279.
  2. Gutman RE, Nygaard IE, Ye W, Rahn DD, Barber MD, Zyczynski HM, Rickey L, Nager CW, Varner RE, Kenton K. The Pelvic Floor Complication Scale: a new instrument for reconstructive pelvic surgery. American journal of obstetrics and gynecology. 2013;208(1):81. e1-. e9.

Extended Colpopexy And Urinary Reduction Efforts (PFDN-E-CARE)

  1. Grimes C, Lukacz ES, Gantz MG, Warren LK, Brubaker L, Zyczynski HM, Richter HE, Jelovsek JE, Cundiff G, Fine P. What happens to the posterior compartment and bowel symptoms after sacrocolpopexy? evaluation of 5-year outcomes from E-CARE. Female pelvic medicine & reconstructive surgery. 2014;20(5):261.
  2. Nygaard I, Brubaker L, Zyczynski HM, Cundiff G, Richter H, Gantz M, Fine P, Menefee S, Ridgeway B, Visco A. Long-term outcomes following abdominal sacrocolpopexy for pelvic organ prolapse. Jama. 2013;309(19):2016-24. 

Outcomes Following Vaginal Prolapse Repair and mid urethral sling (opus) trial (PFDN-OPUS)

  1. Brubaker L, Nager CW, Richter HE, Weidner AC, Hsu Y, Wai CY, Paraiso M, Nolen TL, Wallace D, Meikle S. Effectiveness of blinding: sham suprapubic incisions in a randomized trial of retropubic midurethral sling in women undergoing vaginal prolapse surgery. American journal of obstetrics and gynecology. 2014;211(5):554. e1-. e7.
  2. Wei JT, Nygaard I, Richter HE, Nager CW, Barber MD, Kenton K, Amundsen CL, Schaffer J, Meikle SF, Spino C. A midurethral sling to reduce incontinence after vaginal prolapse repair. New England Journal of Medicine. 2012;366(25):2358-67.

BOOST: Behavioral Therapy Of Obstetric Sphincter Tears (PFDN-BOOST)

  1. Mueller ER, Corton M, Fielding J, Spino C, Jelovsek JE, Weidner A, Zyczynski H, Menefee S, Gantz MG, Tuteja A, Richter HE, Pelvic Floor Disorders Network. Results of a Novel and Comprehensive Training Program for Standardization of 2-Dimensional Ultrasound Interpretation as a Precursor to a Multicenter Trial JJ Med Diagnosis and Image. 2016 May; 1(1): 012.
  2. Richter HE, Nager CW, Burgio KL, Whitworth R, Weidner AC, Schaffer J, Zyczynski HM, Norton P, Jelovsek JE, Meikle SF, Spino C, Gantz M, Graziano S, Brubaker L, Network NPFD. Incidence and Predictors of Anal Incontinence After Obstetric Anal Sphincter Injury in Primiparous Women. Female Pelvic Med Reconstr Surg. 2015;21(4):182-9. doi: 10.1097/SPV.0000000000000160. PubMed PMID: 25679358; PMCID: PMC4481184.

Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial (PFDN-OPTIMAL)

  1. Lukacz ES, Warren LK, Richter HE, Brubaker L, Barber MD, Norton P, Weidner AC, Nguyen JN, Gantz MG. Quality of Life and Sexual Function 2 Years After Vaginal Surgery for Prolapse. Obstetrics & Gynecology. 2016;127(6):1071-9.
  2. Barber MD, Brubaker L, Burgio KL, Richter HE, Nygaard I, Weidner AC, Menefee SA, Lukacz ES, Norton P, Schaffer J. Comparison of 2 transvaginal surgical approaches and perioperative behavioral therapy for apical vaginal prolapse: the OPTIMAL randomized trial. Jama. 2014;311(10):1023-34.
  3. Barber MD, Kenton K, Janz NK, Hsu Y, Dyer KY, Greer WJ, White A, Meikle S, Ye W. Validation of the activities assessment scale in women undergoing pelvic reconstructive surgery. Female pelvic medicine & reconstructive surgery. 2012;18(4):205.
  4. Barber MD, Janz N, Kenton K, Hsu Y, Greer WJ, Dyer K, White A, Meikle S, Ye W. Validation of the surgical pain scales in women undergoing pelvic reconstructive surgery. Female pelvic medicine & reconstructive surgery. 2012;18(4):198.

Anticholinergic vs. Botox Comparison study: The ABC Trial (PFDN-ABC)

  1. Visco AG, Zyczynski H, Brubaker L, Nygaard I, Xu X, Lukacz ES, Paraiso MF, Greer J, Rahn DD, Meikle SF. Cost-Effectiveness Analysis of Anticholinergics Versus Botox for Urgency Urinary Incontinence: Results From the Anticholinergic Versus Botox Comparison Randomized Trial. Female Pelvic Medicine & Reconstructive Surgery. 2016;22(5):311-6.
  2. Visco AG, Brubaker L, Jelovsek JE, Wilson TS, Norton P, Zyczynski HM, Spino C, Sirls L, Nguyen JN, Rahn DD. Adherence to oral therapy for urgency urinary incontinence: results from the Anticholinergic versus Botox Comparison (ABC) trial. Female pelvic medicine & reconstructive surgery. 2016;22(1):24-8.
  3. Pearce MM, Zilliox MJ, Rosenfeld AB, Thomas-White KJ, Richter HE, Nager CW, Visco AG, Nygaard IE, Barber MD, Schaffer J. The female urinary microbiome in urgency urinary incontinence. American journal of obstetrics and gynecology. 2015;213(3):347. e1-. e11.
  4. Brubaker L, Nager CW, Richter HE, Visco A, Nygaard I, Barber MD, Schaffer J, Meikle S, Wallace D, Shibata N. Urinary bacteria in adult women with urgency urinary incontinence. International urogynecology journal. 2014;25(9):1179-84.
  5. Visco AG, Brubaker L, Richter HE, Nygaard I, Paraiso MFR, Menefee SA, Schaffer J, Lowder J, Khandwala S, Sirls L. Anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence. New England Journal of Medicine. 2012;367(19):1803-13.
  6. Visco AG, Brubaker L, Richter HE, Nygaard I, Paraiso MF, Menefee SA, Schaffer J, Wei J, Chai T, Janz N. Anticholinergic versus botulinum toxin A comparison trial for the treatment of bothersome urge urinary incontinence: ABC trial. Contemporary clinical trials. 2012;33(1):184-96.

1. Elmunzer BJ, Serrano J, Chak A, Edmundowicz SA, Papachristou GI, Scheiman JM, Singh VK, Varadurajulu S, Vargo JJ, Willingham FF. Rectal indomethacin alone versus indomethacin and prophylactic pancreatic stent placement for preventing pancreatitis after ERCP: study protocol for a randomized controlled trial. Trials. 2016;17(1):120.

1. Venkat VL, Shneider BL, Magee JC, Turmelle Y, Arnon R, Bezerra JA, Hertel PM, Karpen SJ, Kerkar N, Loomes KM. Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia. Journal of pediatric gastroenterology and nutrition. 2014;59(6):702.

2. Bezerra JA, Spino C, Magee JC, Shneider BL, Rosenthal P, Wang KS, Erlichman J, Haber B, Hertel PM, Karpen SJ. Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial. Jama. 2014;311(17):1750-9.

3. Shneider BL, Magee JC, Bezerra JA, Haber B, Karpen SJ, Raghunathan T, Rosenthal P, Schwarz K, Suchy FJ, Kerkar N. Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia. Pediatrics. 2012;130(3):e607-e14.

1. Foxman B, Cronenwett AE, Spino C, Berger MB, Morgan DM. Cranberry juice capsules and urinary tract infection after surgery: results of a randomized trial. American journal of obstetrics and gynecology. 2015;213(2):194.

2. Marschall J, Piccirillo ML, Foxman B, Zhang L, Warren DK, Henderson JP. Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital. BMC infectious diseases. 2013;13(1):213.

3. Marschall J, Zhang L, Foxman B, Warren DK, Henderson JP. Both host and pathogen factors predispose to Escherichia coli urinary-source bacteremia in hospitalized patients. Clinical infectious diseases. 2012;54(12):1692-8.

1. Baldwin JT, Mann DL. NHLBI's program for VAD therapy for moderately advanced heart failure: the REVIVE-IT pilot trial. Journal of cardiac failure. 2010;16(11):855-8.

2. Pagani FD, Aaronson KD, Kormos R, Mann DL, Spino C, Jeffries N, Taddei-Peters WC, Mancini DM, McNamara DM, Grady KL. The NHLBI REVIVE-IT study: Understanding its discontinuation in the context of current left ventricular assist device therapy. Elsevier; 2016.

1. Maestas MM, Brook RD, Ziemba RA, Li F, Crane RC, Klaver ZM, Bard RL, Spino CA, Adar SD, Morishita M. Reduction of personal PM2.5 exposure via indoor air filtration systems in Detroit: an intervention study. Journal of Exposure Science and Environmental Epidemiology (accepted) (2018).

1. Borello-France D, Burgio KL, Goode PS, Ye W, Weidner AC, Lukacz ES, Jelovsek J-E, Bradley CS, Schaffer J, Hsu Y. Adherence to behavioral interventions for stress incontinence: rates, barriers, and predictors. Physical therapy. 2013;93(6):757.

2. Kenton K, Barber M, Wang L, Meikle S, Hsu Y, Rahn D, Whitcomb E, Amundsen C, Bradley C, Zyczynski H. Pelvic floor symptoms improve similarly after pessary and behavioral treatment for stress incontinence. Female pelvic medicine & reconstructive surgery. 2012;18(2):118.

3. Schaffer J, Nager CW, Xiang F, Borello-France D, Bradley CS, Wu JM, Mueller E, Norton P, Paraiso MFR, Zyczynski H. Predictors of success and satisfaction of nonsurgical therapy for stress urinary incontinence. Obstetrics and gynecology. 2012;120(1):91.

1. Jelovsek JE, Chagin K, Brubaker L, Rogers RG, Richter HE, Arya L, Barber MD, Shepherd JP, Nolen TL, Norton P. A model for predicting the risk of de novo stress urinary incontinence in women undergoing pelvic organ prolapse surgery. Obstetrics and gynecology. 2014;123(2 0 1):279.

2. Gutman RE, Nygaard IE, Ye W, Rahn DD, Barber MD, Zyczynski HM, Rickey L, Nager CW, Varner RE, Kenton K. The Pelvic Floor Complication Scale: a new instrument for reconstructive pelvic surgery. American journal of obstetrics and gynecology. 2013;208(1):81. e1-. e9.

1. Grimes C, Lukacz ES, Gantz MG, Warren LK, Brubaker L, Zyczynski HM, Richter HE, Jelovsek JE, Cundiff G, Fine P. What happens to the posterior compartment and bowel symptoms after sacrocolpopexy? evaluation of 5-year outcomes from E-CARE. Female pelvic medicine & reconstructive surgery. 2014;20(5):261.

2. Nygaard I, Brubaker L, Zyczynski HM, Cundiff G, Richter H, Gantz M, Fine P, Menefee S, Ridgeway B, Visco A. Long-term outcomes following abdominal sacrocolpopexy for pelvic organ prolapse. Jama. 2013;309(19):2016-24.

1. Brubaker L, Nager CW, Richter HE, Weidner AC, Hsu Y, Wai CY, Paraiso M, Nolen TL, Wallace D, Meikle S. Effectiveness of blinding: sham suprapubic incisions in a randomized trial of retropubic midurethral sling in women undergoing vaginal prolapse surgery. American journal of obstetrics and gynecology. 2014;211(5):554. e1-. e7.

2. Wei JT, Nygaard I, Richter HE, Nager CW, Barber MD, Kenton K, Amundsen CL, Schaffer J, Meikle SF, Spino C. A midurethral sling to reduce incontinence after vaginal prolapse repair. New England Journal of Medicine. 2012;366(25):2358-67.

1. Mueller ER, Corton M, Fielding J, Spino C, Jelovsek JE, Weidner A, Zyczynski H, Menefee S, Gantz MG, Tuteja A, Richter HE, Pelvic Floor Disorders Network. Results of a Novel and Comprehensive Training Program for Standardization of 2-Dimensional Ultrasound Interpretation as a Precursor to a Multicenter Trial JJ Med Diagnosis and Image. 2016 May; 1(1): 012.

2. Richter HE, Nager CW, Burgio KL, Whitworth R, Weidner AC, Schaffer J, Zyczynski HM, Norton P, Jelovsek JE, Meikle SF, Spino C, Gantz M, Graziano S, Brubaker L, Network NPFD. Incidence and Predictors of Anal Incontinence After Obstetric Anal Sphincter Injury in Primiparous Women. Female Pelvic Med Reconstr Surg. 2015;21(4):182-9. doi: 10.1097/SPV.0000000000000160. PubMed PMID: 25679358; PMCID: PMC4481184.

1. Lukacz ES, Warren LK, Richter HE, Brubaker L, Barber MD, Norton P, Weidner AC, Nguyen JN, Gantz MG. Quality of Life and Sexual Function 2 Years After Vaginal Surgery for Prolapse. Obstetrics & Gynecology. 2016;127(6):1071-9.

2. Barber MD, Brubaker L, Burgio KL, Richter HE, Nygaard I, Weidner AC, Menefee SA, Lukacz ES, Norton P, Schaffer J. Comparison of 2 transvaginal surgical approaches and perioperative behavioral therapy for apical vaginal prolapse: the OPTIMAL randomized trial. Jama. 2014;311(10):1023-34.

3. Barber MD, Kenton K, Janz NK, Hsu Y, Dyer KY, Greer WJ, White A, Meikle S, Ye W. Validation of the activities assessment scale in women undergoing pelvic reconstructive surgery. Female pelvic medicine & reconstructive surgery. 2012;18(4):205.

4. Barber MD, Janz N, Kenton K, Hsu Y, Greer WJ, Dyer K, White A, Meikle S, Ye W. Validation of the surgical pain scales in women undergoing pelvic reconstructive surgery. Female pelvic medicine & reconstructive surgery. 2012;18(4):198.

1. Visco AG, Zyczynski H, Brubaker L, Nygaard I, Xu X, Lukacz ES, Paraiso MF, Greer J, Rahn DD, Meikle SF. Cost-Effectiveness Analysis of Anticholinergics Versus Botox for Urgency Urinary Incontinence: Results From the Anticholinergic Versus Botox Comparison Randomized Trial. Female Pelvic Medicine & Reconstructive Surgery. 2016;22(5):311-6.

2. Visco AG, Brubaker L, Jelovsek JE, Wilson TS, Norton P, Zyczynski HM, Spino C, Sirls L, Nguyen JN, Rahn DD. Adherence to oral therapy for urgency urinary incontinence: results from the Anticholinergic versus Botox Comparison (ABC) trial. Female pelvic medicine & reconstructive surgery. 2016;22(1):24-8.

3. Pearce MM, Zilliox MJ, Rosenfeld AB, Thomas-White KJ, Richter HE, Nager CW, Visco AG, Nygaard IE, Barber MD, Schaffer J. The female urinary microbiome in urgency urinary incontinence. American journal of obstetrics and gynecology. 2015;213(3):347. e1-. e11.

4. Brubaker L, Nager CW, Richter HE, Visco A, Nygaard I, Barber MD, Schaffer J, Meikle S, Wallace D, Shibata N. Urinary bacteria in adult women with urgency urinary incontinence. International urogynecology journal. 2014;25(9):1179-84.

5. Visco AG, Brubaker L, Richter HE, Nygaard I, Paraiso MFR, Menefee SA, Schaffer J, Lowder J, Khandwala S, Sirls L. Anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence. New England Journal of Medicine. 2012;367(19):1803-13.

6. Visco AG, Brubaker L, Richter HE, Nygaard I, Paraiso MF, Menefee SA, Schaffer J, Wei J, Chai T, Janz N. Anticholinergic versus botulinum toxin A comparison trial for the treatment of bothersome urge urinary incontinence: ABC trial. Contemporary clinical trials. 2012;33(1):184-96.

1. Lisabeth LD, Diex Roux AV, Escobar JD, Smith MA, Morgenstern LB. Neighborhood environment and risk of ischemic stroke. Am J Epidemiol 2007;165:279-287.

2. Brown DL, Al-Senani F, Lisabeth LD, Farnie MA, Colletti LA, Langa KM, Fendrick AM, Garcia NM, Smith MA, Morgenstern LB. Defining cause of death in stroke patients: the Brain Attack Surveillance in Corpus Christi Project. Am J Epidemiol 2007 165:591-596.

3. Gonzales NR, Brown DL, Maddox KE, Conley KM, Espinosa N, Pary JK, Karim AP, Moyé LA, Grotta JC, Morgenstern LB. Kids Identifying and Defeating Stroke (KIDS): Design of a School Based Intervention to Improve Stroke Awareness. Ethn Dis 2007: Spring;17:320-326.

4. Zahuranec DB, Brown DL, Lisabeth LD, Gonzales NR, Longwell PJ, Smith MA, Garcia N, Morgenstern LB. Early care limitations independently predict mortality after intracerebral hemorrhage. Neurology 2007;68:1651-1657.

5. Morgenstern LB, Gonzales NR, Maddox KE, Brown DL, Karim AP, Espinosa N, Moyé LA, Pary JK, Grotta JC, Lisabeth LD, Conley KM. A Randomized, controlled trial to teach middle school children to recognize stroke and call 911: The Kids Identifying and Defeating Stroke project (KIDS). Stroke 2007;38:2972-2978.

6. Majersik JJ, Smith MA, Zahuranec DB, Sánchez BN, Morgenstern LB. Population-based analysis of the impact of expanding the time window for acute stroke treatment. Stroke , Stroke 2007 38:3213-7.

7. Conley, KM, Majersik JJ, Gonzales GR, Maddox KE, Pary JK, Brown DL, Moye LA, Espinosa N, Grotta JC, Morgenstern LB. Kids identifying and defeating stroke (KIDS): Development and implementation of a multi-ethnic health education intervention to increase stroke awareness among middle school students and their parents. Health Promotion Practice , 2008 Mar 10 [Epub ahead of print].

8. Brown DL, Lisabeth LD, Chetcuti SJ, Grossman PM, Alexander T, Pappas JD, Moscucci M, Eagle KA, Garcia NM, Smith MA, Morgenstern LB. Screening for myocardial infarction and ischemic stroke: A population-based study. Neuroepidemiology 2007;29:96-100.

9. Zahuranec DB, Morgenstern LB, Garcia NM, Conley KM, Lisabeth LD, Rank GS, Smith MA, Meurer WJ, Resnicow K, Brown DL. Stroke health and risk education (SHARE) pilot project: feasibility and need for church-based stroke health promotion in a bi-ethnic community. Stroke 2008;39:1583-1585.

10. Lisabeth LD, Peyser PA, Long JC, Majerisk JJ, Smith MA, Morgenstern LB. Stroke among siblings in a bi-ethnic community. Neuroepidemiol 2008;31:33-38.

11. Lisabeth LD, Escobar JD, Dvonch JT, Sanchez BN, Majersik JJ, Brown DL, Smith MA, Morgenstern LB. Ambient air pollution and risk of ischemic stroke and TIA. Ann Neurol2008; 64: 53-59.

12. Lisabeth LD, Smith MA, Sánchez BN, Brown DL. Ethnic disparities in stroke and hypertension among women: the BASIC project. Am J Hypertens 2008; 21:778-783.

13. Eden SV, Meurer WJ, Sánchez BN, Lisabeth LD, Smith MA, Brown DL, Morgenstern LB.Gender and ethnic differences in subarachnoid hemorrhage. Neurology 2008; 2;71:731-735.

14. Meurer WJ, Sánchez BN, Smith MA, Lisabeth LD, Majersik JJ, Brown DL, Uchino K, Bonikowski FP, Mendizabal JE, Zahuranec DB, Morgenstern LB. Predicting ischaemic stroke subtype from presenting systolic blood pressure: the BASIC Project. J Intern Med2009;265:388-396.

15. Morgenstern LB, Escobar JD, Sánchez BN, Hughes R, Zuniga BG, Garcia N, Lisabeth LD. Fast food and neighborhood stroke risk. Ann Neurol 2009; 66:165-170.

16. Zahuranec DB, Brown DL, Lisabeth LD,Gonzales NR, PJ Longwell, Smith MA, Garcia NM, Morgenstern LB. Ethnic differences in do-not-resuscitate orders after intracerebral hemorrhage. Crit Care Med 2009; 37: 2807-2811.

17. Smith MA, Lisabeth LD, Bonikowski F, Morgenstern LB. The role of ethnicity, sex, and language on delay to hospital arrival for acute ischemic stroke. Stroke 2010;41:905-909.

18. Lisabeth LD, Sánchez BN, Escobar J, Hughes R, Meurer WJ, Zuniga B, Garcia N, Brown DL, Morgenstern LB. The food environment in an urban Mexican American community. Health and Place 2010; 16:598-605.

19. Skolarus LE, Sánchez BN, Morgenstern LB, Garcia NM, Smith MA, Brown DL, Lisabeth LD. Validity of proxies and correction for proxy use when evaluating social determinants of health in stroke patients. Stroke 2010;41:510-515.

20. Smith MA, Lisabeth LD, Bonikowski F, Morgenstern LB. The Role of Ethnicity, Sex and Language on Delay to Hospital Arrival for Acute Ischemic Stroke. Stroke 2010; 41:905-909.

21. Cantu-Brito C, Majersik JJ, Sanchez BN Ruano A, Quiñónez G, Arbola J, Morgenstern LB. Hospitalized stroke surveillance in the community of Durango Mexico—the Brain Attack Surveillance in Durango (BASID) Study. Stroke 2010; 41: 878-884.

22. Zahuranec DB, Morgenstern LB, Sánchez BN, Resnicow K, White DB, Hemphill JC 3rd.Do-not-resuscitate orders and predictive models after intracerebral hemorrhage.Neurology. 2010;75:626-633.

23. Simpson JR, Zahuranec DB, Lisabeth LD, Sánchez BN, Skolarus LE, Mendizabal JE, Smith MA, Garcia NM, Morgenstern LB. Mexican Americans with atrial fibrillation have more recurrent strokes than do non-Hispanic whites. Stroke 2010;41:2132-2136.

24. Kerber KA, Burke JF, Brown DL, Meurer WJ, Smith MA, Lisabeth LD, Morgenstern LB, Zahuranec DB. Does intracerebral hemorrhage mimic benign dizziness presentations? A population based study. Emerg Med J 2012; 29: 43-46.

25. Cantu-Brito C, Majersik JJ, Sánchez BN, Ruano A, Becerra-Mendoza D, Wing JJ, Morgenstern LB. Door-to-Door Capture of Incident and Prevalent Stroke Cases in Durango, Mexico: The Brain Attack Surveillance in Durango Study. Stroke 2011;42:601-606.

26. Skolarus LE, Lisabeth LD, Sánchez BN, Smith MA, Garcia NM, Risser, Morgenstern LB.The Prevalence of Spirituality, Optimism, Depression, and Fatalism in a Bi-ethnic Stroke Population. J Relig Health 2010 Dec 24. [Epub ahead of print]

27. Lisabeth LD, Morgenstern LB, Wing JJ, Sanchez BN, Zahuranec DB, Skolarus LE, Burke JF, Kleerekoper M, Smith MA, Brown DL. Poststroke Fractures in A Bi-ethnic Community. J Stroke Cerebrovasc Dis 2011 Feb 18. [Epub ahead of print]

28. Lisabeth LD, Morgenstern LB, Burke DT, Sun YV, Long JC. Ancestral heterogeneity in a biethnic stroke population. Ann Hum Genet. 2011;75:508-515.

29. Morgenstern, LB, Sánchez BN, Skolarus LE, Garcia N, Risser JMH, Wing JJ, Smith MA, Zahuranec DB, Lisabeth LD. Fatalism, optimism, spirituality, depressive symptoms and stroke outcome: A population-based analysis. Stroke 2011;42:3518-3523.

30. Skolarus LE, Lisabeth LD, Morgenstern LB, Burgin W, Brown DL. Sleep Apnea Risk Among Mexican American and Non-Hispanic White Stroke Survivors. Stroke 2012;43:1143-1145.

31. Sealy-Jefferson S, Wing JJ, Sánchez BN, Brown DL, Meurer WJ, Smith MA, Morgenstern LB, Lisabeth LD. Age- and Ethnic-Specific Sex Differences in Stroke Risk.Gend Med 2012; 9: 121-128.

1. Lisabeth LD, Brown DL, Hughes R, Majersik JJ, Morgenstern LB. (2009). Acute Stroke Symptoms Comparing Women and Men. Stroke, 2031-2036.

2. Brown DL, Feskanich D, Sanchez BN, Rexrode KM, Schernhammer ES, Lisabeth LD. (2009). Rotating Night Shift Work and Risk of Ischemic Stroke. American Journal of Epidemiology, 169, 1370-1377.

3. Reeves M, Bhatt A, Jajou P, Brown M, Lisabeth LD. (2009). Sex Differences in the Use of Intravenous rt-PA Thrombolysis Treatment for Acute Ischemic Stroke. A Meta-Analysis. Stroke, 40, 1743-1749.

4. Lisabeth LD, Diez-Roux, A.V., Escobar, J.D., Smith, M.A., Morgenstern, L.B. (2007). Neighborhood Environments and Risk of Ischemic Stroke: The Brain Attack Surveillance in Corpus Christi Project (BASIC). American Journal of Epidemiology, 165, 279-287.

1. Alasubramanian P, Sirivelu MP, Weiss KA, Wagner JG, Harkema JR, Morishita M, Mohankumar PS, Mohankumar SM. (2013) Differential effects of inhalation exposure to PM(2.5) on hypothalamic monoamines and corticotrophin releasing hormone in lean and obese rats. Neurotoxicology. 36:106-111. PubMed PMID: 22426024.

2. Blazek A, Rustky J, Osei K, Maiseyeu A, Sanjay Rajagopalan. (2013) Exercise-mediated changes in high-density lipoprotein: Impact on form and function. American Heart Journal. 166(3):392-400. PubMed PMID: 24016485.

3. Brook RD, Bard RL, Kaplan MJ, Yalavarthi S, Morishita M, Dvonch JT, Wang L, Yang HY, Spino C, Mukherjee B, Oral EA, Sun Q, Brook JR, Harkema J, Rajagopalan S. (2013) The effect of acute exposure to coarse particulate matter air pollution in a rural location on circulating endothelial progenitor cells: results from a randomized controlled study. Inhal Toxicol. 25(10):587-592. PubMed PMID: 23919441.

4. Brook RD, Xu X, Bard RL, Dvonch JT, Morishita M, Kaciroti N, Sun Q, Harkema J, Rajagopalan S. (2013) Reduced metabolic insulin sensitivity following sub-acute exposures to low levels of ambient fine particulate matter air pollution. Sci
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5. Brook RD, Bard RL, Morishita M, Dvonch JT, Wang L, Yang HY, Spino C, Mukherjee B, Kaplan MJ, Yalavarthi S, Oral EA, Ajluni N, Sun Q, Brook JR, Harkema J, Rajagopalan S. (2014) Hemodynamic, Autonomic, and Vascular Effects of Exposure to Coarse Particulate Matter Air Pollution from a Rural Location. Environ Health Perspect; 122; 624-30. PubMed PMID: 24618231.

6. Byrd JB, Morishita M, Bard RL, Das R, Wang L, Sun Z, Spino C, Harkema J, Dvonch JT, Rajagopalan S, Brook RD (2016). Acute increase in blood pressure during inhalation of coarse particulate matter air pollution from an urban location. Am Soc Hypertens. 10(2):133-139.e4. PubMed PMID: 26750378.

7. Kumagai K, Lewandowski R, Jackson-Humbles DN, Li N, Van Dyken SJ, Wagner JG, Harkema JR (2015). Ozone-induced Nasal Type 2 Immunity in Mice is Dependent on Innate Lymphoid Cells. Am J Respir Cell Mol Biol. [Epub ahead of print] PubMed PMID: 26559808.

8. Liu C, Bai Y, Xu X, Sun L, Wang A., Wang TY, Maurya SK, Periasamy M, Morishita M, Harkema J, Ying Z, Sun Q, Rajagopalan S. (2014) Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus. Particle Fibre Toxicol. 11:27. PubMed PMID: 24886175.

9. Liu C, Xu X, Bai Y, Wang TY, Rao X, Wang A, Sun L, Ying Z, Gushchina L, Maiseyeu A, Morishita M, Sun Q, Harkema JR, Rajagopalan S. 2014. Air Pollution-Mediated Susceptibility to Inflammation and Insulin Resistance: Influence of CCR2 Pathways in Mice. Environ Health Perspect. 122:17-26. PubMed PMID: 24149114.

10. Liu C, Zheing Y, Harkema J, Sun Q, Rajagopalan S. (2013) Epidemiological and Experimental Links between Air Pollution and Type 2 Diabetes. Toxicol Pathol. 41(2):361-373. PubMed PMID: 23104765.

11. Maiseyeu A, Yang HY, Ramanathan G, Yin F, Bard RL, Morishita M, Dvonch JT, Wang L, Spino C, Mukherjee B, Badgeley MA, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo JA, Brook RD. (2014) No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function. Inhal Toxicol. 26(1):23-9. PubMed PMID: 24417404.

12. Morishita M, Bard RL, Kaciroti N, Fitzner CA, Dvonch T, Harkema JR, Rajagopalan S, Brook RD. (2014) Exploration of the composition and sources of urban fine particulate matter associated with same-day cardiovascular health effects in Dearborn, Michigan. J Expo Sci Environ Epidemiol [Epub ahead of print] PubMed PMID: 24866265.

13. Morishita M, Bard RL, Wang L, Das R, Dvonch JT, Spino C, Mukherjee B, Sun Q, Harkema JR, Rajagopalan S, Brook RD. (2014) The characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures. J Expo Sci Environ Epidemiol. PubMed PMID: 25227729.

14. Ong CB, Kumagai K, Brooks PT, Brandenberger C, Lewandowski RP, Jackson-Humbles DN, Nault R, Zacharewski TR, Wagner JG, Harkema JR.(2015). Ozone-Induced Type 2 Immunity in Nasal Airways: Development and Lymphoid Cell Dependence in Mice. Am J Respir Cell Mol Biol. [Epub ahead of print] PubMed PMID: 26203683.

15. Pancras JP, Landis MS, Norris GA, Vedantham R, Dvonch JT. (2013) Source apportionment of ambient fine particulate matter in Dearborn, Michigan, using hourly resolved PM chemical composition data. Sci Total Environ. 448:2-13. PubMed PMID:23302684.

16. Rao X, Zhong J, Maiseyeu A, Gopalakrishnan B, Villamena FA, Chen LC, Harkema JR, Sun Q, Rajagopalan S. (2014) CD36-Dependent 7-Ketocholesterol Accumulation in Macrophages Mediates Progression of Atherosclerosis in Response to Chronic Air Pollution Exposure. Circ Res. PubMed PMID: 25186795.

17. Sun L, Liu C, Xu X, Ying Z, Maiseyeu A, Wang A, Allen K, Lewandowski RP, Bramble LA, Morishita M, Wagner JG, Dvonch JT, Sun Z, Yan X, Brook RD, Rajagopalan S, Harkema JR, Sun Q, Fan Z. (2013) Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet. Part Fibre Toxicol. 10(1):43. PubMed PMID: 23968387. PMCID:PMC3765456.

18. Wagner JG, Kamal AS, Morishita M, Dvonch JT, Harkema J, Rohr AC. (2014) PM2.5-induced cardiovascular dysregulation in rats is associated with elemental carbon and temperature-resolved carbon subfractions. Particle Fibre Toxicol. 11:25. PubMed PMID: 24885999.

19. Wagner JG, Allen K, Yang HY, Nan B, Morishita M, Mukherjee B, Dvonch JT, Spino C, Fink GD, Rajagopalan S, Sun Q, Brook RD, Harkema JR. (2014) Cardiovascular Depression in Rats Exposed to Inhaled Particulate Matter and Ozone: Effects of Diet-Induced Metabolic Syndrome. Environ Health Perspect. 122: 27-33. PubMed PMID: 24169565.

20. Ying Z, Xu X, Bai Y, Zhong J, Chen M, Liang Y, Zhao J, Liu D, Morishita M, Sun Q, Spino C, Brook RD, Harkema JR, Rajagopalan S. (2014) Long-Term Exposure to Concentrated Ambient PM2.5 Increases Mouse Blood Pressure through Abnormal Activation of the Sympathetic Nervous System: A Role for Hypothalamic Inflammation. Environ Health Perspect. 122: 79-86. PubMed PMID: 24240275.

21. Ying Z, Xu X, Chen M, Liu D, Zhong M, Chen LC, Sun Q, Rajagopalan S. (2013) A Synergistic Vascular Effect of Airborne Pariculate Matter and Nickel in a Mouse Model. Toxicol Sci. PubMed PMID: 23788629.

22. Ying Z, Allen K, Zhong J, Chen M, Williams KM, Wagner JG, Lewandowski R, Sun Q, Rajagopalan S, Harkema JR. (2016) Subacute inhalation exposure to ozone induces systemic inflammation but not insulin resistance in a diabetic mouse model. Inhal Toxicol. 4:155-63. PubMed PMID: 26986950.

23. Zhong J, Allen K, Rao X, Ying Z, Braunstein Z, Kankanala SR, Xia C, Wang X, Bramble LA, Wagner JG, Lewandowski R, Sun Q, Harkema JR, Rajagopalan S. (2016) Repeated Ozone Exposure Exacerbates Insulin Resistance And Activates Innate Immune Response In Genetically Susceptible Mice. Inhal Toxicol. 1-10. [Epub ahead of print] PubMed PMID: 27240593.

1. Shneider BL, Magee JC, Karpen SJ, Rand EB, Narkewicz MR, Bass LM, Schwarz K, Whitington PF, Bezerra JA, Kerkar N, Haber B, Rosenthal P, Turmelle YP, Molleston JP, Murray KF, Ng VL, Wang KS, Romero R, Squires RH, Arnon R, Sherker AH, Moore J, Ye W, Sokol RJ, Childhood Liver Disease Research Network Chi L.Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia. J Pediatr. 2016;170:211-7 e2. PubMed PMID: 26725209.

2. Karjoo S, Hand NJ, Loarca L, Russo PA, Friedman JR, and Wells RG. Extra-Hepatic Cholangiocyte Cilia are Abnormal in Biliary Atresia. Journal of Pediatric Gastroenterology and Nutrition. 2013; 57(1): 96-101.

3. Karjoo S, Wells RG. Isolation of Neonatal Extrahepatic Cholangiocytes. Journal of Visualized Experiments. 2014; 5(88): video.

4. Wang KS, Moss RL, Caty MG, Davidoff A, Fallat ME, Heiss KF, Holcomb G 3rd, Meyers RL, Watterberg KL, Aucott S, Benitz WE, Cummings JJ, Eichenwald EC, Goldsmith J, Poindexter BB, Puopolo K, Stewart DL, Wang KS, Kerkar N, Karpen SJ, Sokol RJ, Schwarz KB, Mogul DB, Harpavat S. Newborn Screening for Biliary Atresia. Pediatrics. 2015 Dec; 136(6):e1663-9. doi: 10.1542/peds.2015-3570.

5. Leung D, Ye W, Molleston J, Weymann A, Ling S, Paranjape S, Romero R, Schwarzenberg SJ, Palermo J, Alonso E, Murray K, Marshall B, Sherker A, Siegel M, Krishnamurthy R, Harned R, Karmazyn B, Magee J C, Narkewicz MR on behalf of the Cystic Fibrosis Liver Disease Network (CFLD NET). Baseline ultrasound and clinical correlates in children with Cystic Fibrosis. J Pediatrics. 2015 Oct; 167(4): 862-868.

6. Kamath BM, Chen Z, Romero R, Fredericks EM, Alonso EM, Arnon R, Heubi J, Hertel PM, Karpen SJ, Loomes KM, Murray KF, Rosenthal P, Schwarz KB, Subbarao G, Teckman JH, Turmelle YP, Wang KS, Sherker AH, Sokol RJ, Magee JC; Childhood Liver Disease Research Network (ChiLDReN). Quality of Life and its Determinants in a Multi-Center Cohort of Children with Alagille Syndrome. J Pediatrics. 2015 Aug;167(2):390-396.

7. Ogawa M, Ogawa S, Bear CE, Ahmadi S, Chin S, Li B, Grompe M, Keller G, Kamath BM, Ghanekar A.Directed differentiation of cholangiocytes from human pluripotent stem cells. Nat Biotechnol. 2015 Aug; 33(8):853.61.

8. Teckman JH, Rosenthal P, Abel R, Bass LM, Michail S, Murray KF, Rudnick DA, Thomas DW, Spino C, Arnon R, Hertel PM, Heubi J, Kamath BM, Karnsakul W, Loomes KM, Magee JC, Molleston JP, Romero R, Shneider BL, Sherker AH, Sokol RJ. Baseline Analysis of a Young Alpha-1-AT Deficiency Liver Disease Cohort Reveals Frequent Portal Hypertension. JPGN. 2015 (epub ahead of print).

9. Coughlin CR, Scharer GH, Friederich MW, Yu HC, Geiger EA, Creadon-Swindell G, Collins AE, Vanlander AV, Coster RV, Powell CA, Swanson MA, Minczuk M, Van Hove JL, Shaikh TH. Mutations in the mitochondrial cysteinyl-tRNA synthase gene, CARS2, lead to a severe epileptic encephalopathy and complex movement disorder. J Med Genet. 2015 (epub ahead of print).

10. Tsai EA, Grochowski CM, Falsey AM, Rajagopalan R, Wendel D, Devoto M, Krantz ID, Loomes KM, Spinner NB. Heterozygous Deletion of FOXA2 Segregates with Disease in a Family with Heterotaxy, Panhypopituitarism, and Biliary Atresia Human Mutation. 2015; 36(6): 631-7.

11. Lorent K, Gong W, Koo AK, Waisbourd-Zinman O, Karjoo S, Sealy I, Kettleborough RN, Stemple DL, Ueno Y, Windsor PA, Whittaker SJ, Porter JR, Wells RG, Pack M. Identification of a Plant Isoflavonoid that Causes Biliary Atresia. Sci Trans Med. 2015; 7(286):286ra67.

12. Wen Ye, Phil Rosenthal, John Magee and Peter Whitington. Factors Determining Delta-Bilirubin Levels in Biliary Atresia Infants. JPGN. 2015; 60(5):659-63.

13. Venkat VL, Shneider BL, Magee JC, Turmelle Y, Arnon R, Bezerra JA, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston J, Murray KF, Ng VL, Raghunathan T, Rosenthal P, Schwartz K, Sherker AH, Sokol RJ, Teckman J, Wang K, Whitington PF, Heubi JE; Childhood Liver Disease Research and Education Network.Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia. JPGN. 2014; 59(6):702-7.

14. Ng, Vicky Lee; Haber, Barbara H; Magee, John C; Miethke, Alexander; Murray, Karen F; Michail, Sonia; Karpen, Saul J; Kerkar, Nanda; Molleston, Jean P; Romero, Rene; Rosenthal, Philip; Schwarz, Kathleen B; Shneider, Benjamin L; Turmelle, Yumirle P; Alonso, Estella M; Sherker, Averell H; Sokol, Ronald J; Childhood Liver Disease Research and Education Network (CHiLDREN). Medical status of 219 children with biliary atresia surviving long-term with their native livers: results from a North American multicenter consortium. J Pediatr. 2014; 165(3):539-546.

15. Heubi JE, Setchell KD, Jha P, Buckley D, Zhang W, Rosenthal P, Potter C, Horslen S, Suskind D. Treatment of bile acid amidation defects with glycocholic acid. Hepatology. 2015; 61(1):268-74.

16. Bessho, Kazuhiko; Mourya, Reena; Shivakumar, Pranavkumar; Walters, Stephanie; Magee, John C; Rao, Marepalli; Jegga, Anil G; Bezerra, Jorge A. Gene expression signature for biliary atresia and a role for interleukin-8 in pathogenesis of experimental disease. Hepatology. 2014; 60(1):211-23.

17. Bezerra, Jorge A; Spino, Cathie; Magee, John C; Shneider, Benjamin L; Rosenthal, Philip; Wang, Kasper S; Erlichman, Jessi; Haber, Barbara; Hertel, Paula M; Karpen, Saul J; Kerkar, Nanda; Loomes, Kathleen M; Molleston, Jean P; Murray, Karen F; Romero, Rene; Schwarz, Kathleen B; Shepherd, Ross; Suchy, Frederick J; Turmelle, Yumirle P; Whitington, Peter F; Moore, Jeffrey; Sherker, Averell H; Robuck, Patricia R; Sokol, Ronald J; Childhood Liver Disease Research and Education Network (ChiLDREN). Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial. JAMA. 2014; 311(17):1750-9.

18. Sambrotta, Melissa; Strautnieks, Sandra; Papouli, Efterpi; Rushton, Peter; Clark, Barnaby E; Parry, David A; Logan, Clare V; Newbury, Lucy J; Kamath, Binita M; Ling, Simon; Grammatikopoulos, Tassos; Wagner, Bart E; Magee, John C; Sokol, Ronald J; Mieli-Vergani, Giorgina; University of Washington Center for Mendelian Genomics; Smith, Joshua D; Johnson, Colin A; McClean, Patricia; Simpson, Michael A; Knisely, A S; Bull, Laura N; Thompson, Richard J. Mutations in TJP2 cause progressive cholestatic liver disease Nat Genet. 2014; 46(4):326-8.

19. Tsai EA, Grochowski CM, Loomes KM, Bessho K, Hakonarson H, Bezerra JA, Russo PA, Haber BA, Spinner NB, Devoto M. Replication of a GWAS signal in a Caucasian population implicates ADD3 in susceptibility to biliary atresia Hum Genet. 2014; 133(2):235-43.

20. Cui, S., Leyva-Vega, M., Tsai, E. A., EauClaire, S. F., Glessner, J. T., Hakonarson, H., Devoto, M., Haber, B. A., Spinner, N. B., Matthews, R. P. Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility gene. Gastroenterology. 2013; 144(5):1107-15.

21. K. D. Setchell, J. E. Heubi, S. Shah, J. E. Lavine, D. Suskind, M. Al-Edreesi, C. Potter, D. W. Russell, N. C. O'Connell, B. Wolfe, P. Jha, W. Zhang, K. E. Bove, A. S. Knisely, A. F. Hofmann, P. Rosenthal and L. N. Bull.Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. Gastroenterology. 2013; 144(5):945-55.

22. Mealer M, Kittelson J, Thompson BT, Wheeler AP, Magee JC, Sokol RJ, Moss M, and. Kahn MG. Remote source document verification in two national clinical trials networks: A pilot study. PLoS One. 2013; 8(12).

23. Mack CL, Anderson KM, Aubrey MT, Rosenthal P, Sokol RJ and Freed BM. Lack of HLA predominance and HLA shared epitopes in biliary Atresia. SpringerPlus. 2013; 2(1):1-13.

24. Molleston JP, Sokol RJ, Karnsakul W, Miethke A, Horslen S, Magee JC, Romero R, Squires RH and Van Hove JL for Childhood Liver Disease Research and Education Network. Evaluation of the child with suspected mitochondrial liver disease J Pediatr Gastroenterol Nutr. 2013; 57(3):269-276.

25. Schwarz KB, Haber BH, Rosenthal P, Mack CL, Moore J, Bove, K, Bezerra JA, Karpen SJ, Kerkar N, Shneider BL, Turmelle YP, Whitington PF, Molleston JP, Murray KF, Ng VL, Romero R, Wang KS, Sokol RJ and Magee JC for Childhood Liver Disease Research and Education Network. Extra-hepatic anomalies in infants with biliary atresia: results of a large prospective North American multi-center study. Hepatology. 2013; 58(5):1724-31.

26. Sundaram SS, Alonso EM, Haber B, Magee JC, Fredericks E, Kamath B, Kerkar N, Rosenthal P, Shepherd R, Limbers C, Varni JW, Robuck P and Sokol RJ for Childhood Liver Disease Research and Education Network.Health related Quality of Life in patients with biliary atresia surviving with their native liver. J Pediatr. 2013; 163(4):1052-7.

27. Brindley SM, Lanham AM, Karrer FM, Tucker RM, Fontenot AP and Mack CL. Cytomegalovirus-specific T-cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells.Hepatology. 2012; 55(4):1130-1138.

28. Chu AS, Russo PA and Wells RG. Cholangiocyte cilia are abnormal in syndromic and non-syndromic biliary atresia. Mod Pathol. 2012; 25(5):751-757.

29. Kamath BM, Bauer RC, Loomes KM, Chao G, Gerfen J, Hutchinson A, Hardikar W, Hirschfield G, Jara P, Krantz ID, Lapunzina P, Leonard L, Ling S, Ng VL, Hoang PL, Piccoli DA and Spinner NB. NOTCH2 mutations in Alagille syndrome. J Med Genet. 2012; 49(2):138-144.

30. Mack CL, Feldman AG and Sokol RJ. Clues to the etiology of bile duct injury in biliary atresia. Semin Liver Dis. 2012; 32(4):307-316.

31. Kamath BM, Piccoli DA, Magee JC, and Sokol RJ for Childhood Liver Disease Research and Education Network. Pancreatic insufficiency is not a prevalent problem in Alagille syndrome. J Pediatr Gastroenterol Nutr. 2012; 55(5):612-614.

32. Penton AL, Leonard LD and Spinner NB. Notch signaling in human development and disease. Semin Cell Dev Biol. 2012; 23(4):450-457.

33. Sheridan RM, Gupta A, Miethke A, Knisely AS and Bove KE. (Letter to the editor) Multiple dysplastic liver nodules in PFIC2 underscore risk for neoplasia associated with functional BSEP deficiency. Am J Surg Pathol. 2012; 36(5):785-786.

34. Shneider BL, Abel RB, Haber B, Karpen SJ, Magee JC, Romero R, Schwarz K, Bass LM, Kerkar N, Miethke AG, Rosenthal P, Turmelle Y, Robuck PR and Sokol RJ for Childhood Liver Disease Research and Education Network. Portal hypertension in children and young adults with biliary atresia. J Pediatr Gastroenterol Nutr. 2012; 55(5):567-573.

35. Shneider BL, Magee JC, Bezerra JA, Haber B, Karpen SJ, Raghunathan T, Rosenthal P, Schwarz K, Suchy FJ, Kerkar N, Turmelle Y, Whitington PF, Robuck PR and Sokol RJ for Childhood Liver Disease Research and Education Network (ChiLDREN). Efficacy of fat soluble vitamin supplementation in infants with biliary atresia: a prospective multi-center analysis. Pediatrics. 2012; 130(3):e607-614.

36. Zahm AM, Hand NJ, Boateng LA and Friedman JR. Circulating microRNA is a biomarker of biliary atresia.J Pediatr Gastroenterol Nutr. 2012; 55(4):366-369.

37. Bessho K and Bezerra JA. Biliary atresia: will blocking inflammation tame the disease? Annu Rev Med. 2011; 62(X):171-185.

38. Chu AS, Diaz R, Hui JJ, Yanger K, Zong Y, Alpini G, Stanger BZ and Wells RG. Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis. Hepatology. 2011; 53(5):1685-1695.

39. Evason K, Bove KE, Finegold MJ, Knisely AS, Rhee S, Rosenthal P, Miethke AG, Karpen SJ, Ferrell LD and Kim GE. Morphologic findings in Progressive Familial Intrahepatic Cholestasis 2 (PFIC2): Correlation with genetic and immunohistochemical studies. Am J Surg Path. 2011; 35(5):687-696.

40. He M, Pei Z, Mohsen AW, Watkins P, Murdoch G, Van Veldhoven PP, Ensenauer R and Vockley J.Identification and characterization of new long chain acyl-CoA dehydrogenases. Mol Genet Metab. 2011; 102(4):418-429.

41. Li J, Bessho K, Shivakumar P, Mourya R, Mohanty SK, Dos Santos JL, Miura IK, Porta G and Bezerra JA. Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype. J Clin Invest. 2011; 121(11):4244-4256.

42. Russo P, Magee JC, Boitnott J, Bove KE, Raghunathan T, Finegold M, Haas J, Jaffe R, Kim GE, Magid M, Melin-Aldana H, White F, Whitington PF, Sokol RJ for the Biliary Atresia Research Consortium. Design and validation of the Biliary Atresia Research Consortium histologic assessment system for cholestasis in infancy. Clin Gastroenterology and Hepatol. 2011; 9(4):357-362.

43. Saxena V, Shivakumar P, Sabla G, Mourya R, Chougnet C and Bezerra JA. Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia. Nature Rev Gastroenterol Hepatol 2011;8:660. Sci Transl Med. 2011; 3(102):102ra194.

44. Shin S, Walton G, Aoki R, Brondell K, Schug J, Fox A, Smirnova O, Dorrell C, Erker L, Chu AS, Wells RG, Grompe M, Greenbaum LE and Kaestner KH. Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev. 2011; 25(11):1185-1192.

45. Superina R, Magee JC, Brandt ML, Healey PJ, Tiao G, Ryckman F, Karrer FM, Iyer K, Fecteau A, West K, Burns RC, Flake A, Lee H, Lowell JA, Dillon P, Colombani P, Ricketts R, Li Y, Moore J and Wang KS. for Childhood Liver Disease Research and Education Network (ChiLDREN). The anatomic pattern of biliary atresia identified at time of Kasai Hepatoportoenterostomy and early postoperative clearance of jaundice are significant predictors of transplant-free survival. Ann Surg. 2011; 254(4):577-585.

46. Leyva-Vega M, Gerfen J, Thiel BD, Jurkiewicz D, Rand EB, Pawlowska J, Kaminska D, Russo P, Gai X, Krantz ID, Kamath BM, Hakonarson H, Haber BA and Spinner NB. Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3. Am J Med Genet A. 2010; 152A(4):886-895.

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48. Moyer K, Kaimal V, Pacheco C, Mourya R, Xu H, Shivakumar P, Chakraborty R, Rao M, Magee JC, Bove K, Aronow BJ, Jegga AG and Bezerra JA. Staging of biliary atresia at diagnosis by molecular profiling of the liver. Genome Med. 2010; 2(5):33.

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53. Griggs RC, Batshaw M, Dunkle M, Gopal-Srivastava R, Kaye E, Krischer J, Nguyen T, Paulus K and Merkel PA.Clinical research for rare disease: opportunities, challenges, and solutions. Mol Genet Metab. 2009; 96(1):20-26.

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1. Han SH, Reddy KR, Keeffe EB, Soldevila-Pico C, Gish R, Chung RT, Degertekin B, Lok A; NIH HBV OLT Study Group. Clinical outcomes of liver transplantation for HBV-related hepatocellular carcinoma: data from the NIH HBV OLT study. Clin Transplant. 2011 Mar-Apr;25(2):E152-62. doi: 10.1111/j.1399-0012.2010.01349.x. Epub 2010 Nov 16. PubMed PMID: 21077950; PubMed Central PMCID: PMC3771871.

2. Degertekin B, Han SH, Keeffe EB, Schiff ER, Luketic VA, Brown RS Jr, Emre S, Soldevila-Pico C, Reddy KR, Ishitani MB, Tran TT, Pruett TL, Lok AS; NIH HBV-OLT Study Group. Impact of virologic breakthrough and HBIG regimen on hepatitis B recurrence after liver transplantation. Am J Transplant. 2010 Aug;10(8):1823-33. doi: 10.1111/j.1600-6143.2010.03046.x. Epub 2010 Mar 23. PubMed PMID: 20346062; PubMed Central PMCID: PMC2910807.

3. Bzowej N, Han S, Degertekin B, Keeffe EB, Emre S, Brown R, Reddy R, Lok AS; National Institutes of Health Hepatitis B Virus Orthotopic Liver Transplantation Study Group. Liver transplantation outcomes among Caucasians, Asian Americans, and African Americans with hepatitis B. Liver Transpl. 2009 Sep;15(9):1010-20. doi: 10.1002/lt.21759. PubMed PMID: 19718627; PubMed Central PMCID: PMC4438268.

4. Ito K, Kim KH, Lok AS, Tong S. Characterization of genotype-specific carboxyl-terminal cleavage sites of hepatitis B virus e antigen precursor and identification of furin as the candidate enzyme. J Virol. 2009 Apr;83(8):3507-17. doi: 10.1128/JVI.02348-08. Epub 2009 Feb 4. PubMed PMID: 19193799; PubMed Central PMCID: PMC2663268.

5. Lok AS. How to diagnose and treat hepatitis B virus antiviral drug resistance in the liver transplant setting. Liver Transpl. 2008 Oct;14 Suppl 2:S8-S14. doi: 10.1002/lt.21616. Review. PubMed PMID: 18825720.

6. Gaglio P, Singh S, Degertekin B, Ishitani M, Hussain M, Perrillo R, Lok AS; National Institutes of Health Hepatitis B Virus-Orthotopic Liver Transplantation Study Group. Impact of the hepatitis B virus genotype on pre- and post-liver transplantation outcomes. Liver Transpl. 2008 Oct;14(10):1420-7. doi: 10.1002/lt.21563. PubMed PMID: 18825703.

7. Osborn MK, Han SH, Regev A, Bzowej NH, Ishitani MB, Tran TT, Lok AS; NIH HBV-OLT Study Group. Outcomes of patients with hepatitis B who developed antiviral resistance while on the liver transplant waiting list. Clin Gastroenterol Hepatol. 2007 Dec;5(12):1454-61. Epub 2007 Oct 31. PubMed PMID: 17977800; PubMed Central PMCID: PMC2645788.

8. Hussain M, Soldevila-Pico C, Emre S, Luketic V, Lok AS; NIH HBV-OLT Study Group. Presence of intrahepatic (total and ccc) HBV DNA is not predictive of HBV recurrence after liver transplantation. Liver Transpl. 2007 Aug;13(8):1137-44. PubMed PMID: 17663390.

9. Degertekin B, Lok AS. When to start and stop hepatitis B treatment: can one set of criteria apply to all patients regardless of age at infection? Ann Intern Med. 2007 Jul 3;147(1):62-4. PubMed PMID: 17606963.

10. Lok AS, Zoulim F, Locarnini S, Bartholomeusz A, Ghany MG, Pawlotsky JM, Liaw YF, Mizokami M, Kuiken C; Hepatitis B Virus Drug Resistance Working Group. Antiviral drug-resistant HBV: standardization of nomenclature and assays and recommendations for management. Hepatology. 2007 Jul;46(1):254-65. Review. PubMed PMID: 17596850.

11. Lok AS. Navigating the maze of hepatitis B treatments. Gastroenterology. 2007 Apr;132(4):1586-94. Epub 2007 Feb 24. Review. Erratum in: Gastroenterology. 2007 Dec;133(6):2077. PubMed PMID: 17408643.

 

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