Nicaraguan Pediatric Influenza Cohort Study
This cohort study of ~1,800 Nicaraguan children designed to examine the burden of influenza in children and development of immunity. Children are enrolled at birth and followed to age 15. In 2020, the 10th year of the study, the cohort was expanded to investigate SARS-CoV-2 natural history and immunity. Because the cohort was started in 2011 and SARS-CoV-2 testing was established in February 2020, the cohort is uniquely situated to examine immunity to SARS-CoV-2 and endemic human coronaviruses.
This study is funded by the National Institute of Allergy and Infectious Disease (NIAID).