Andrew F. Brouwer, PhD, M.S., M.A.

Andrew Brouwer is mathematical epidemiologist and modeler. He is currently an Assistant Research Scientist in the Department of Epidemiology at the University of Michigan. Andrew uses mathematical and statistical modeling to address public health problems in infectious disease, cancer, and tobacco control. He is a faculty affiliate in the Center for Study of Complex Systems. Andrew holds graduate degrees in mathematics, statistics, and environmental science and engineering.

• PhD, Applied and Interdisciplinary Mathematics, University of Michigan, 2015
• M.A., Statistics, University of Michigan, 2015
• M.S., Applied and Interdisciplinary Mathematics, University of Michigan, 2013
• M.S., Environmental Science and Engineering, Clarkson University, 2011
• M.A., Mathematics, SUNY College at Potsdam, 2009
• B.A., Mathematics, Chemistry, SUNY College at Potsdam, 2009

Andrew uses mathematical and statistical modeling to address public health problems. He works on a wide range of topics in infectious disease, cancer prevention and survival, and tobacco control using an array of computational and statistical tools. Rigorous consideration of parameter identifiability, parameter estimation, and uncertainty quantification are underlying themes in Andrew’s work.

Modeling and epidemiology of enteric pathogens

• Brouwer AF, Eisenberg MC, Shulman LM, Famulare M, Koopman JS, Kroiss SJ, Hindiyeh M, Manor Y, Grotto I, Eisenberg JNS. (2022). The role of time-varying viral shedding in modelling environmental surveillance for public health: revisiting the 2013 poliovirus outbreak in Israel. Journal of the Royal Society Interface.
• Espira LM*, Brouwer AF*, Han BA, Foufopoulos J, Eisenberg JNS. (2021). Dilution of epidemic potential of environmentally transmitted infectious diseases for species with partially overlapping habitats. American Naturalist. *co-first author
• Brouwer AF, Eisenberg JNS, Pomeroy CD, Shulman LM, Hindiyeh M, Manor Y, Grotto I, Koopman JS, Eisenberg MC. (2018). Epidemiology of the silent polio outbreak in Rahat, Israel based on modeling of environmental surveillance data. Proceedings of the National Academy of Science.
• Brouwer AF, Weir MH, Meza R, Eisenberg MC, Eisenberg JNS. (2017). Dose-response relationships for environmentally mediated infectious disease transmission models. PLOS Computational Biology.

Modeling and epidemiology the human papillomavirus

• Brouwer AF, Campredon LP, Walline HM, Marinelli BM, Goudsmit CM, Thomas TB, Delinger RL, Lau YK, Andrus EC, Nair T, Carey TE, Eisenberg MC, Meza R. (2022). Incidence and clearance of oral and cervicogenital HPV infection: longitudinal analysis of the MHOC cohort study. BMJ Open.
• Brouwer AF*, Delinger RL*, Eisenberg MC, Campredon LP, Walline HM, Carey TE, Meza R. (2019). HPV vaccination has not increased sexual activity or accelerated sexual debut in a college-aged cohort of men and women. BMC Public Health. *co-first author
• Brouwer AF, Meza R, Eisenberg MC. (2019). Integrating measures of viral prevalence and seroprevalence: a mechanistic modeling approach to explaining cohort patterns of HPV in women in the U.S. Journal of the Royal Society: Philosophical Transactions B.
• Brouwer AF, Eisenberg MC, Carey TE, Meza R. (2019). Multisite HPV infections in the United States (NHANES 2003-2014): an overview and synthesis. Preventive Medicine.

Epidemiology and modeling of other infectious diseases

• Brouwer AF, Balmaseda A, Gresh L, Patel M, Ojeda S, Schiller AJ, Lopez R, Webby RJ, Nelson MI, Kuan G, Gordon A. (2022). Birth cohort relative to an influenza A virus's antigenic cluster introduction drives patterns of children's antibody titers. PLOS Pathogens.
• Brouwer AF, Zelner JL, Eisenberg MC, Kimmins L, Ladisky M, Eisenberg JNSE. (2020). The impact of vaccination efforts on the spatiotemporal patterns of the hepatitis A outbreak in Michigan, 2016–18. Epidemiology.
• Brouwer AF, Myers JL, Martin ET, Konopka KE, Lauring AS, Eisenberg MC, Lephart PR, Nguyen T, Jaworski A, Schmidt CJ. (2020). Severe Acute Respiratory Syndrome Coronavirus 2 Surveillance in Decedents in a Large, Urban Medical Examiner's Office. Clinical Infectious Diseases.
• Kraay ANM, Brouwer AF, Lin N, Collender PA, Remais JV, Eisenberg JNS. (2018). Modeling environmentally mediated rotavirus transmission: The role of temperature and hydrologic factors. Proceedings of the National Academy of Science.

Models of carcinogenesis and cancer survival

• Brouwer AF, He K, Chinn SB, Mondul AM, Chapman CH, Ryser MD, Banerjee M, Eisenberg MC, Meza R, Taylor JMG. (2020). Time‐varying survival effects for squamous cell carcinomas at oropharyngeal and nonoropharyngeal head and neck sites in the United States, 1973‐2015. Cancer.
• Brouwer AF, Eisenberg MC, Meza R. (2018). Case Studies of Gastric, Lung, and Oral Cancer Connect Etiologic Agent Prevalence to Cancer Incidence. Cancer Research.
• Brouwer AF, Meza R, Eisenberg MC. (2017). Parameter estimation for multistage clonal expansion models from cancer incidence data: a practical identifiability analysis. PLOS Computational Biology.
• Brouwer AF, Eisenberg MC, Meza R. (2016). Age effects and temporal trends in HPV-related and HPV-unrelated oral cancer in the United States: A multistage carcinogenesis modeling analysis. PLOS One.

Trends and transitions in tobacco product use

• Brouwer AF, Levy DT, Jeon J, Jimenez-Mendoza E, Sanchez-Romero LM, Mistry R, Meza R. (2022). The impact of current tobacco product use definitions on estimates of transitions between cigarette and ENDS use. Nicotine & Tobacco Research.
• Brouwer AF, Jeon J, Cook SF, Usidame B, Hirschtick JL, Jimenez-Mendoza E, Mistry R, Flesicher NL, Holford TR, Mendez D, Levy DT, Meza R. (2022). The impact of menthol cigarette flavor in the US: cigarette and ENDS transitions by sociodemographic group. American Journal of Preventive Medicine.
• Tam J, Brouwer AF. (2021). Comparison of e-cigarette use prevalence and frequency by smoking status among youth in the United States, 2014-2019. Addiction.
• Brouwer AF, Jeon J, Hirschtick JL, Jimenez-Mendoza E, Mistry R, Bondarenko IV, Land SR, Holford TR, Levy DT, Taylor JMG, Fleischer NL, Meza R. (2020). Transitions between cigarette, ENDS, and dual use in adults in the PATH study (Waves 1–4): multistate transition modeling accounting for complex survey design. Tobacco Control.

Society of Mathematical Biology
Society for Industrial and Applied Mathematics
Rogel Cancer Center: Cancer Epidemiology & Prevention