Description: This course presents the basic skills to design and analyze functional magnetic resonance imaging (fMRI) experiments. We start by reviewing the basic Matlab and Unix skills necessary to manipulate image data. Next we introduce the principles of MRI and the nature of the Blood Oxygenation Level Dependent (BOLD) effect, including artifacts that corrupt the BOLD signal. We cover blocked and event-related designs, and how to optimize statistical power of design. We cover subject safety.