UM-CEHC Publications


ELEMENT Publication List: 

  1. Hernández-Avila M, Gonzalez-Cossio T, Palazuelos E, Romieu I, Aro A, Fishbien E, Peterson KE, Hu H. Dietary and environmental determinants of blood and bone lead levels in lactating postpartum women living in Mexico City. Environ Health Perspect. 1996 Oct;104(10):1076-82.  [Link] [PDF]

  2. González-Cossío T, Peterson KE, Sanín LH, Fishbein E, Palazuelos E, Aro A, Hernández-Avila M, Hu H. Decrease in birth weight in relation to maternal bone-lead burden. Pediatrics. 1997 Nov;100(5):856-62.  [Link] [PDF]

  3. González-Cossío T, Sanín LH, Hernández-Avila M, Rivera J, Hu H. Longitud y peso al nacer: El papel de la nutrición materna [Length and weight at birth: The role of maternal nutritional status.] Salud Pública Mex [Public Health in Mexico]. 1998;40:119-126.  [Link] [PDF]

  4. Hernández-Avila M, Smith D, Meneses F, Sanin LH, Hu H. The influence of bone and blood lead on plasma lead levels in environmentally exposed adults. Environ Health Perspect. 1998 Aug;106(8):473-7.  [Link] [PDF]

  5. Hu H. Bone lead as a new biologic marker of lead dose: Recent findings and implications for public health. Environ Health Perspect. 1998 Aug;106(Suppl 4):961-7.  [Link] [PDF]

  6. Brown MJ, Hu H, Gonzales-Cossio T, Peterson KE, Sanín LH, de Luz Kageyama M, Palazuelos E, Aro A, Schnaas L, Hernandez-Avila M. Determinants of bone and blood lead concentrations in the early postpartum period. Occup Environ Med. 2000;57:535-541.  [Link] [PDF]

  7. Chuang HY, Hu H, Schwartz J, Palazuelos E, Aro A, Amarasiriwardena C, Hernandez-Avila M. Interrelations of lead levels in bone, venous blood, and umbilical cord with exogenous lead exposure through maternal plasma lead in peripartum women. Environ Health Perspect. 2001 May;109(5):527-32.  [Link] [PDF]

  8. Sanín LH, González-Cossío T, Roemieu I, Peterson KE, Ruíz S, Palazuelos E, Hernández-Avila M, Hu H. Effect of maternal lead burden on infant weight and weight gain at one-month of age among breastfed infants. Pediatrics. 2001;107:1016-1023.      [Link] [PDF]

  9. Téllez-Rojo MM, Hernández-Avila M, González-Cossio T, Romieu I, Aro A, Palazuelos E, Schwartz J, Hu H. Impact of breastfeeding on the mobilization of lead from bone. Am J Epidemiol. 2002 Mar 1;155(5):420-8.  [Link]

  10. Smith D, Hernández-Avila M, Téllez-Rojo MM, Mercado A, Hu H. The relationship between lead in plasma and whole blood in women. Environ Health Perspect. 2002 Mar;110(3):263-8.  [Link] [PDF]

  11. Gomaa A, Hu H, Bellinger D, Schwartz J, Tsaih SW, Gonzalez-Cossio T, Schnaas L, Peterson K, Aro A, Hernández-Avila M. Maternal bone lead as an independent risk factor for fetal neurotoxicity: a prospective study. Pediatrics. 2002 Jul;110(1 Pt 1):110-8.  [Link] [PDF

  12. Hu H, Hernandez-Avila M. Invited commentary: lead, bones, women and pregnancy – the poison within? Am J Epidemol. 2002 Dec 15;156(2):1088-91. [Link] [PDF]

  13. Hernández-Avila M, Peterson KE, Gonzalez-Cossio T, Sanín LH, Aro A, Schnaas L, Hu H. Effect of maternal bone lead on length and head circumference of newborns and 1-month-old infants. Arch Environ Health. 2002 Sep-Oct;57(5):482-8.  [Link] [PDF]

  14. Hernández-Avila M, Gonzalez-Cossio T, Hernández-Avila JE, Romieu I, Peterson KE, Aro A, Palazuelos E, Hu H. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology. 2003 Mar;14(2):206-12.  [Link] [PDF]

  15. Janakiraman V, Ettinger A, Mercado-Garcia A, Hu H, Hernández-Avila M. Calcium supplements and bone resorption in pregnancy: a randomized crossover-trial. Am J Prev Med. 2003 Apr;24(3):260-4.  [Link] [PDF]

  16. Guerra-Tamayo JL, Hernandez-Cadena L, Téllez-Rojo MM, Mercado-García Adel S, Solano-González M, Hernández-Avila M, Hu H. [Time to pregnancy and lead exposure]. Salud Publica Mex. 2003;45 Suppl 2:198-95.  [Link] [PDF]

  17. Ettinger AS, Téllez-Rojo MM, Amarasiriwardena C, Gonzalez-Cossio T, Peterson K, Aro A, Hu H, Hernández-Avila M. Levels of lead in breast milk and their relation to maternal blood and bone lead levels and one month postpartum. Environ Health Perspect. 2004 Jun;112(8):926-31.  [Link] [PDF]

  18. Ettinger AS, Téllez-Rojo MM, Amarasiriwardena C, Bellinger D, Peterson K, Schwartz J, Hu H, Hernández-Avila M. Effect of breast milk lead on infant blood lead levels at 1 month of age. Environ Health Perspect. 2004 Oct;112(14):1381-5.  [Link] [PDF]

  19. Téllez-Rojo MM, Hernández-Avila M, Lamadrid-Figueroa H, Smith D, Hernández-Cadena L, Mercado A, Aro A, Schwartz J, Hu H. Impact of bone lead and bone resorption on plasma and whole blood lead levels during pregnancy. Am J Epidemiol. 2004 Oct;160(7):668-78.  [Link] [PDF]

  20. Sánchez BN, Budtz-Jorgensen E, Ryan LM, Hu H. Structural equation models. a review with applications to environmental epidemiology. J Am Stat Assoc. 2005;100:1443-1455.  [Link] [PDF]

  21. Ettinger AS, Téllez-Rojo MM, Amarasiriwardena C, Peterson KE, Schwartz J, Aro A, Hu H, Hernández-Avila M. Influence of maternal bone lead burden and calcium intake on levels of lead in breast milk over the course of lactation. Am J Epidemiol. 2006 Jan 1;163(1):48-56. [Link] [PDF]

  22. Jarrell FJ, Weisskopf MG, WEuve J, Téllez-ROjo MM, Hu H, Hernández-Avila M. Maternal lead exposure and the secondary sex ratio. Hum Reprod. 2006 Jul;21(7):1901-6. [Link] [PDF]

  23. Téllez-Rojo MM, Bellinger D, Arroyo-Quiroz C, Lamadrid-Figueroa L, Mercado-Garcia A, Schnaas-Arrieta L, Wright RO, Hernández-Avila M, Hu H. Longitudinal associations between blood lead concentrations lower than 10 microg/dL and neurobehavioral development in environmentally exposed children in Mexico City. Pediatrics. 2006 Aug;118(2):e323-e330. [Link] [PDF]

  24. Lamadrid-Figueroa H, Téllez-Rojo MM, Hernández-Cadena L, Mercado-Garcia A, Smith D, Solano-Gonzalez M, Hernández-Avila M, Hu H. Biological markers of fetal lead exposure at each stage of pregnancy. J Toxicol Environ Health A. 2006 Oct;69(19):1781-96. [Link] [PDF]

  25. Hu H, Téllez-Rojo MM, Bellinger D, Smith D, Ettinger AS, Lamadrid-Figueroa H, Schwartz J, Schnaas L, Mercado-Garcia A, Hernández-Avila M. Fetal lead exposure at each stage of pregnancy as a predictor of infant mental development. Environ Health Perspect. 2006 Nov;114(11):1730-5. [Link] [PDF]

  26. Ettinger AS, Hu H, Hernández-Avila M. Dietary calcium supplementation to lower blood lead levels in pregnancy and lactation. J Nutr Biochem. 2007 Mar;18(3):172-8. [Link] [PDF]

  27. Lamadrid-Figueroa H, Téllez-Rojo MM, Hernández-Avila M, Trejo-Valdivia B, Solano-Gonzalez M, Mercado-Garcia A, Smith D, Hu H, Wright RO. Association between the plasma/whole blood lead ratio and history of spontaneous abortion: a nested cross-sectional study. BMC Pregnancy Childbirth. 2007 Sep;7:22. [Link] [PDF]

  28. Arora M, Ettinger AS, Peterson KE, Schwartz J, Hu H, Hernández-Avila M, Téllez-Rojo MM, Wright RO. Maternal dietary intake of polyunsaturated fatty acids modifies the relationship between lead levels in bone and breast milk. J Nutr. 2008 Jan;138(1):73-9. [Link] [PDF]

  29. Surkan PJ, Schnaas L, Wright RJ, Téllez-Rojo MM, Lamadrid-Figueroa H, Hu H, Hernández-Avila M, Bellinger DC, Schwartz J, Perroni E, Wright RO. Maternal self-esteem, exposure to lead, and child neurodevelopment. Neurotoxicology. 2008 Mar;29(2):278-85. [Link] [PDF]

  30. Hopkins MR, Ettinger AS, Hernández-Avila M, Schwartz J, Téllez-Rojo MM, Lamadrid-Figueroa H, Bellinger D, Hu H, Wright RO. Variants in iron metabolism genes predict higher blood lead levels in young children. Environ Health Perspect. 2008 Sep;116(9):1261-6. [Link] [PDF]

  31. Avendaño-Badillo D, Hernández-Avila M, Hernández-Cadena L, Rueda-Hernández G, Solano-González M, Ibarra LG, Hu H, Téllez-Rojo MM. High dietary calcium intake decreases bone mobilization during pregnancy in humans. Salud Publica Mex. 2009;51 Suppl 1;S100-7. [Link] [PDF]

  32. Ettinger AS, Lamadrid-Figueroa H, Téllez-Rojo MM, Mercado-Garcia A, Peterson KE, Schwartz J, Hu H, Hernández-Avila M. Effect of calcium supplementation on blood lead levels in pregnancy: a randomized placebo-controlled trial. Environ Health Perspect. 2009 Jan;117(1):26-31. [Link] [PDF]

  33. Sánchez BN, Houseman EA, Ryan LM. Residual-based diagnostics for structural equation models. Biometrics. 2009 Mar;65(1):104-115. [Link] [PDF]

  34. Sánchez BN, Budtz-Jørgensen E, Ryan LM. An estimating equations approach to fitting latent exposure models with longitudinal health outcomes. Annals of Applied Statistics. 2009 Jun;3(2):830-856. [Link] [PDF]

  35. Kordas K, Ettinger AS, Lamadrid-Figueroa H, Téllez-Rojo MM, Hernández-Avila M, Hu H, Wright RO. Methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and G1793A genotypes, and the relationship between maternal folate intake, tibia lead and infant size at birth. Br J Nutr. 2009 Sep;102(6):907-14. [Link] [PDF]

  36. Pilsner JR, Hu H, Ettinger A, Sánchez BN, Wright RO, Cantonwine, D, Lazarus A, Lamadrid-Figueroa H, Mercado-Garcia A, Téllez-Rojo MM, Hernández-Avila M. Influence of prenatal lead exposure on genomic methylation of cord blood DNA. Environ Health Perspect. 2009 Sep;117(9):1466-71. [Link] [PDF]

  37. Meeker JD, Hu H, Cantonwine DE, Lamadrid-Figueroa H, Calafat AM, Ettinger AS, Hernández-Avila M, Loch-Caruso R, Téllez-Rojo MM. Urinary phthalate metabolites in relation to preterm birth in Mexico City. Environ Health Perspect. 2009 Oct;117(10):1587-92. [Link] [PDF]

  38. Cantonwine D, Hu H, Téllez-Rojo MM, Sánchez BN, Lamadrid-Figueroa H, Ettinger AS, Mercado-Garcia A, Hernández-Avila M, Wright RO. HFE gene variants modify the association between maternal lead burden and infant birthweight: a prospective birth cohort study in Mexico City, Mexico. Environ Health. 2010 Jul;9:43. [Link] [PDF]

  39. Pilsner JR, Hu H, Wright RO, Kordas K, Ettinger AS, Sánchez BN, Cantonwine D, Lazarus AL, Cantoral A, Schnaas L, Téllez-Rojo MM, Hernández-Avila M. Maternal MTHFR genotype and haplotype predict deficits in early cognitive development in a lead-exposed birth cohort in Mexico City. Am J Clin Nutr. 2010 Jul;92(1):226-34. [Link] [PDF]

  40. Claus Henn B, Ettinger AS, Schwartz J, Téllez-Rojo MM, Lamadrid-Figueroa H, Hernández-Avila M, Schnaas L, Amarasiriwardena C, Bellinger DC, Hu H, Wright RO. Early postnatal blood manganese levels and children's neurodevelopment. Epidemiology. 2010 Jul;21(4):433-9. [Link] [PDF]

  41. Cantonwine D, Meeker JD, Hu H, Sánchez BN, Lamadrid-Figueroa H, Mercado-Garica A, Fortenberry GZ, Calafat AM, Téllez-Rojo MM. Bisphenol A exposure in Mexico City and risk of prematurity: a pilot nested case control study. Environ Health. 2010 Oct 18;9:62. [Link] [PDF]

  42. Cantonwine D, Hu H, Sánchez BN, Lamadrid-Figueroa H, Smith D, Ettinger AS, Mercado-García A, Hernández-Avila M, Wright RO, Téllez-Rojo MM. Critical windows of fetal lead exposure: adverse impacts on length of gestation and risk of premature delivery. J Occup Environ Med. 2010 Nov;52(11):1106-11. [Link] [PDF]

  43. Lamardrid-Figueroa H, Téllez-Rojo MM, Angeles G, Hernández-Avila M, Hu H. Bias correction by use of errors-in-variables regression models in studies with K-X-ray fluorescence bone lead measurements. Environ Res. 2011;111(1):17-20. [Link] [PDF]

  44. Kordas K, Ettinger AS, Bellinger DC, Schnaas L, Téllez-Rojo MM, Hernández-Avila M, Hu H, Wright RO. A Dopamine Receptor (DRD2) but not Dopamine Transporter (DAT1) gene polymorphism is associated with neurocognitive development of Mexican preschool children with lead exposure. J Pediatr. 2011 Oct;159(4):638-43. [Link] [PDF]

  45. Afeiche M, Peterson KE, Sánchez BN, Cantonwine D, Lamadrid-Figueroa H, Schnaas L, Ettinger AS, Hernández-Avila M, Hu H, Téllez-Rojo MM. Prenatal lead exposure and weight of 0 to 5 year-old children in Mexico City. Environ Health Perspect. 2011;119(10):1436-41. [Link] [PDF]

  46. Sánchez BN, Hu H, Litman HJ, Téllez-Rojo MM. Statistical methods to study timing of vulnerability with sparsely sampled data on environmental toxicants. Environ Health Perspect. 2011;119(3):409-15. [Link] [PDF]

  47. Claus Henn B, Kim J, Wessling-Resnick M, Téllez-Rojo MM, Jayawardene I, Ettinger AS, Hernández-Avila M, Schwartz J, Christiani DC, Hu H, Wright RO. Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models. Environ Health. 2011 Nov 10;10:97-107. [Link] [PDF]

  48. Claus Henn B, Schnaas L, Ettinger AS, Schwartz J, Lamadrid-Figueroa H, Hernández-Avila M, Amarasiriwardena C, Hu H, Bellinger DC, Wright RO, Téllez-Rojo MM. Associations of early childhood manganese and lead coexposure with neurodevelopment. Environ Health Perspect. 2012 Jan;120(1):126-31. [Link] [PDF]

  49. Zhang A, Hu H, Sánchez BN, Ettinger AS, Park SK, Cantonwine D, Schnaas L, Wright RO, Lamadrid-Figueroa H, Téllez-Rojo MM. Association between prenatal lead exposure and blood pressure in children. Environ Health Perspect. 2012; Mar;120(3):445-50. [Link] [PDF]

  50. Afeiche M, Peterson KE, Sánchez BN, Schnaas L, Cantonwine D, Ettinger AS, Solano-González M, Hernández-Avila M, Hu H, Téllez-Rojo MM. Windows of lead exposure sensitivity, attained height and body mass index at 48 months. J Pediatr. 2012;160(6):1044-9. [Link] [PDF]

  51. Sánchez BN, Kang S, Mukherjee B. A latent variable approach to study gene-environment interactions in the presence of multiple correlated exposures. Biometrics. 2012 Jun;68(2):466-76. [Link] [PDF]

  52. Braun JM, Hoffman E, Schwartz J, Sanchez B, Schnaas L, Mercado-Garcia A, Solano-Gonzalez M, Bellinger DC, Lanphear BP, Hu H, Tellez-Rojo MM, Wright RO, Hernandez-Avila M. Assessing windows of susceptibility to lead-induced cognitive deficits in Mexican children. Neurotoxicology. 2012 Oct;33(5):1040-7. [Link] [PDF]

  53. Téllez-Rojo MM, Cantoral A, Cantonwine DE, Schnaas L, Peterson KE, Hu H, Meeker JD. Prenatal urinary phthalate metabolites levels and neurodevelopment in children at two and three years of age. Sci Total Environ. 2013 Sep;461-462:386-90. [Link] [PDF]

  54. Lewis RC, Meeker JD, Peterson KE, Lee JM, Cantoral A, Téllez-Rojo MM. Predictors of urinary bisphenol A and phthalate metabolite concentrations in Mexican children. Chemosphere. 2013 Nov;93(10):2390-8. [Link] [PDF]

  55. Fortenberry GZ, Meeker JD, Sánchez BN, Barr DB, Panuwet P, Bellinger D, Schnaas L, Solano-González M, Ettinger AS, Hernández-Avila M, Hu H, Téllez-Rojo MM. Urinary 3, 5, 6-trichloro-2-pyridinol (TCPY) in pregnant women from Mexico City: distribution, temporal variability, and relationship with child attention and hyperactivity. Int J Hyg Environ Health. 2014;217(2-3):405-12. [Link] [PDF]

  56. Ettinger AS, Roy A, Amarasiriwardena CJ, Smith D, Luopli N, Mercado-Garcia A, Lamadrid-Figueroa H, Tellez-Rojo MM, Hu H, Hernández-Avila M. Maternal blood, plasma, and breast milk lead: lactational transfer and contribution to infant exposure. Environ Health Perspect. 2014 Jan;122(1):87-92. [Link] [PDF]

  57. Arora M, Austin C, Sarrafpour B, Hernández-Ávila M, Hu H, Wright RO, Tellez-Rojo MM. Determining prenatal, early childhood and cumulative long-term lead exposure using micro-spatial deciduous dentine levels. PLoS One. 2014 May 19;(9)5:e97805. [Link] [PDF]

  58. Ferguson KK, Peterson KE, Lee JM, Mercado-Garia A, Blank-Goldenberg C, Téllez-Rojo MM, Meeker JD. Prenatal and peripubertal phthalates and bisphenol-A in relation to sex hormones and puberty in boys. Reprod Toxicol. 2014 Aug;47;70-6. [Link] [PDF

  59. Watkins DJ, Téllez-Rojo MM, Ferguson KK, Lee JM, Solano-González M, Blank-Goldenberg C, Peterson KE, Meeker JD. In utero and peripubertal exposure to phthalates and BPA in relation to female sexual maturation. Environ Res. 2014 Oct;134:233-41. [Link] [PDF]

  60. Basu N, Tutino R, Zhang Z, Cantonwine DE, Goodrich JM, Somers EC, Rodriguez L, Schnaas L, Solano-González M, Mercardo-Garcia A, Peterson K, Sánchez BN, Hernández-Avila M, Hu H, Téllez-Rojo MM. Mercury levels in pregnant women, children, and seafood from Mexico City. Environ Res. 2014 Nov;135:63-9. [Link] [PDF

  61. Ettinger AS, Lamadrid-Figueroa H, Mercado-García A, Kordas K, Wood RJ, Peterson KE, Hu H, Hernández-Avila M, Téllez-Rojo MM. Effect of calcium supplementation on bone resorption in pregnancy and the early postpartum: a randomized control trial in Mexican women. Nutr J. 2014 Dec 16;13(1):116. [Link] [PDF]

  62. Tao Y, Sánchez BN, Mukherjee B. Latent variable models for gene-environment interactions in longitudinal studies with multiple correlated exposures. Stat Med. 2015 Mar 30;34(7):1227-41. [Link] [PDF]

  63. Cantoral A, Téllez-Rojo MM, Shamah-Levey T, Schnaas L, Hernández-Ávila M, Peterson KE, Ettinger AS. Prediction of serum zinc levels in Mexican children at 2 years of age using a food frequency questionnaire and different zinc bioavailability criteria. Food Nutr Bull. 2015 Jun;36(2):111-9. [Link] [PDF]

  64. Xu J, Hu H, Wright R, Sánchez BN, Schnaas L, Bellinger DC, Park SK, Martínez S, Hernández-Avila M, Téllez-Rojo MM, Wright RO. Prenatal lead exposure modifies the impact of maternal self-esteem on children's inattention behavior. J Pediatr. 2015 Aug;167(2):435-41. [Link] [PDF]

  65. Cantoral A, Téllez-Rojo MM, Shamah-Levy T, Hernández-Ávila M, Schnaas L, Hu H, Peterson KE, Ettinger AS. Differential association of blood lead on length by serum zinc status in two year old Mexican children. Environ Health. 2015;14:95. [Link] [PDF

  66. Roberts, EFS. Food is love: And so, what then? BioSocieties. 2015;10:247-252. [Link] [PDF]

  67. Liu Y, Peterson KE. Maternal exposure to synthetic chemicals and obesity in offspring: Recent findings. Curr Environ Health Rep. 2015 Dec;2(4):339-47. [Link] [PDF]

  68. Yang TC, Peterson KE, Meeker JD, Sánchez BN, Zhang Z, Cantoral A, Solano M, Tellez-Rojo MM. Bisphenol A and phthalates in utero and in childhood: association with child BMI z-score and adiposity. Environ Res. 2015;156:326-33. [Link] [PDF]

  69. Goodrich JM, Sánchez BN, Dolinoy DC, Zhang Z, Hernández-Ávila M, Hu H, Peterson KE, Téllez-Rojo MM. Quality control and statistical modeling for environmental epigenetics: A study on in utero lead exposure and DNA methylation at birth. Epigenetics. 2016 Jan 2;10(1):19-30. [Link] [PDF]

  70. Watkins DJ, Peterson KE, Ferguson KK, Mercado-Garcia A, Ortiz MT, Cantrol A, Meeker JD, Téllez-Rojo MM. Relating phthalate and BPA exposure to metabolism in peripubescence: the role of exposure timing, sex, and puberty. J Clin Endocrinol Metab. 2016 Jan;101(1):79-88. [Link] [PDF]

  71. Cantoral A, Téllez-Rojo MM, Ettinger AS, Hu H, Hernández-Avila M, Peterson KE. Early introduction and cumulative consumption of sugar-sweetened beverages during the pre-school period and risk of obesity at 8-14 years of age. Pediatr Obes. 2016 Feb;11(1):68-74. [Link] [PDF]

  72. Watkins DJ, Fortenberry GZ, Sánchez BN, Barr DB, Panuwet P, Bellinger D, Schnaas L, Solano-González M, Ettinger AS, Hernández-Avila M, Hu H, Meeker JD, Téllez-Rojo MM. Urinary 3-phenoxybenozic acid (3-PBA) in pregnant women from Mexico City: Distribution and relationships with child neurodevelopment. Environ Res. 2016 May;147:307-13. [Link] [PDF]

  73. Tamayo y Ortiz M, Téllez-Rojo MM, Hu H, Hernández-Ávila M, Wright R, Amarasiriwardena C, Lupoli N, Mercado-García A, Pantic I, Lamardrid-Figueroa H. Lead in candy consumed and blood lead levels of children living in Mexico City. Environ Res. 2016 May;147:497-502. [Link] [PDF]

  74. Huang S, Hu H, Sánchez BN, Peterson KE, Ettinger AS, Lamadrid-Figueroa H, Schnaas L, Mercado-García A, Wright RO, Basu N, Cantonwine DE, Hernández-Avila M, Téllez-Rojo MM. Childhood blood lead levels and symptoms of Attention Deficit Disorder: a cross-sectional study of Mexican children. Environ Health Perspect. 2016 Jun;124(6):868-74. [Link] [PDF]

  75. Kasper N, Peterson KE, Zhang Z, Ferguson KK, Sánchez BN, Cantoral A, Meeker JD, Téllez-Rojo MM, Powlowski CM, Ettinger AS. Association of bisphenol A exposure with breastfeeding and perceived insufficient milk supply in Mexican women. Matern Child Health J. 2016 Aug;20(8):1713-9. [Link] [PDF]

  76. Goodrich JM, Dolinoy DC, Sánchez BN, Zhang Z, Meeker J, Mercado-Garcia A, Solano-Gonzalez M, Hu H, Téllez-Fojo MM, Peterson KE. Adolescent epigenetic profiles and environmental exposures from early life through peri-adolescence. Environmental Epigenetics. 2016;2(3):dvw018. [Link] [PDF]

  77. Thomas DB, Basu N, Martinez-Mier EA, Sánchez BN, Zhang Z, Liu Y, Parajuli RP, Peterson KE, Mercado-Garcia A, Bashash M, Hernández-Avila M, Hu H, Téllez-Rojo MM. Urinary and plasma fluoride levels in pregnant women from Mexico City. Environ Res. 2016;150:489-95. [Link] [PDF]

  78. Somers EC, Monrad SU, Warren JS, Solano M, Schnaas L, Hernandez-Avila M, Tellez-Rojo MM, Hu H. Antinuclear antibody prevalence in a general pediatric cohort from Mexico City: discordance between immunofluorescence and multiplex assays. Clin Epidemiol. 2016:9:1-8. [Link] [PDF]

  79. Moynihan M, Peterson KE, Cantoral A, Song PXK, Jones A, Solano-Gonzalez M, Meeker JD, Basu N, Téllez-Rojo MM. Dietary predictors of urinary cadmium among pregnant women and children. Sci Total Environ. 2017 Jan 1;575:1255-1262. [Link] [PDF]

  80. Zhou Y, Wang P, Xang X, Zhu J, Song PX. Sparse multivariate factor analysis regression models and its applications to integrative genomics analysis. Genet Epidemiol. 2017 Jan;41(1):70-80. [Link] [PDF]

  81. Sánchez BN, Kim S, Sammel MD. Estimators for longitudinal latent exposure models: examining measurement model assumptions. Stat Med. 2017 Jun;36(1):2048-2066. [Link] [PDF]

  82. Perng W, Watkins DJ, Cantoral A, Mercado-Garcia A, Meeker JD, Téllez-Rojo MM, Peterson KE. Exposure to phthalates is associated with lipid profile in peripubertal Mexican youth. Environ Res. 2017;154:311-7. [Link] [PDF]

  83. Chavarro JE, Watkins DJ, Afeiche MC, Zhang Z, Sánchez BN, Cantonwine D, Mercado-Garcia A, Blank-Goldenberg C, Meeker JD, Téllez-Rojo MM, Peterson KE. Validity of self-assessed sexual maturation against physician assessments and hormone levels. J Pediatr. 2017 Jul;186:172-8. [Link] [PDF]

  84. Perng W, Hector EC, Song PXK, Tellez-Rojo MM, Ranskind S, Kachman M, Cantoral A, Burant CF, Peterson KE. Metabolomic determinants of metabolic risk in Mexican adolescents. Obesity (Silver Spring). 2017 Sept;25(9):1594-1602. [Link] [PDF

  85. Watkins DJ, Sánchez BN, Téllez-Rojo MM, Lee JM, Mercado-García A, Blank-Goldenberg C, Peterson KE, Meeker JD. Impact of phthalate and BPA exposure during in utero windows of susceptibility on reproductive hormones and sexual maturation in peripubertal males. Environ Health. 2017 Jun 21;16(1):69. [Link] [PDF]

  86. Watkins DJ, Sánchez BN, Téllez-Rojo MM, Lee JM, Mercado-Garcia A, Blank-Goldenberg C, Peterson KE, Meeker JD. Phthalate and bisphenol A exposure during in utero windows of susceptibility in relation to reproductive hormones and sexual maturation in peripubertal girls. Environ Res. 2017 Nov;159:143-151. [Link] [PDF]

  87. Bashash M, Thomas D, Hu H, Martinez-Mier A, Sánchez BN, Basu N, Peterson KE, Ettinger AS, Wright R, Zhang Z, Liu Y, Schnaas L, Mercado-Garcia A, Téllez-Rojo MM, Hernández-Avila M. Prenatal fluoride exposure and cognitive outcomes in children at 4 and 6-12 years of age in Mexico. Environ Health Perspect. 2017 Sep19;125(9):097017. [Link] [PDF]

  88. Perng W, Fernandez C, Peterson KE, Zhang Z, Cantoral A, Sánchez BN, Solano-González M, Téllez-Rojo MM, Baylin A. Dietary patterns exhibit sex-specific associations with adiposity and metabolic risk in a cross-sectional study in urban Mexican adolescents. J Nutr. 2017 Oct;147(10):1977-1985. [Link] [PDF]

  89. Roberts, EFS. What gets inside: Violent entanglements and toxic boundaries in Mexico City. Cultural Anthropology. 2017;32(4):592-619. [Link] [PDF]

  90. Jansen EC, Zhou L, Perng W, Song PX, Rojo MMT, Mercado A, Peterson KE, Cantoral A. Vegetables and lean proteins-based and processed meats and refined grains -based dietary patterns in early childhood are associated with pubertal timing in a sex-specific manner: a prospective study of children from Mexico City. Nutrition research (New York, NY). 2018;56:41-50. [Link] [PDF]

  91. Al-Hinai M*, Baylin A, Tellez-Rojo M, Cantoral A, Ettinger A, Solano-Gonzalez M, Peterson KE, Perng W. Maternal Intake of Omega-3 and Omega-6 Polyunsaturated Fatty Acids During Mid-Pregnancy is Inversely Associated with Linear Growth. Journal of Developmental Origins of Health and Disease 2018. [Link] [PDF]

  92. Perng W, Baek J, Zhou CW, Cantoral A, Tellez-Rojo MM, Song PX, Peterson KE. Associations of the infancy body mass index peak with anthropometry and cardiometabolic risk in Mexican adolescents. Annals of human biology. 2018 Jul 4;45(5):386-94.  [Link] [PDF]

  93. Baek J, Zhu B, Song PX. Bayesian analysis of infant’s growth dynamics with in utero exposure to environmental toxicants. The Annals of Applied Statistics. 2019;13(1):297-320. [Link]

  94. Ashrap P, Sánchez BN, Téllez-Rojo MM, Basu N, Tamayo-Ortiz M, Peterson KE, Meeker JD, Watkins DJ. In utero and peripubertal metals exposure in relation to reproductive hormones and sexual maturation and progression among girls in Mexico City. Environmental Research. 2019 Oct 1;177:108630. [Link] [PDF]

  95. Ashrap, P., Meeker, J.D., Sánchez, B.N. et al. In utero and peripubertal metals exposure in relation to reproductive hormones and sexual maturation and progression among boys in Mexico City. Environmental Health. 2020 Nov. 25;  19:124. [Link] [PDF]

  96. Rygiel CA, Dolinoy DC, Perng W, Jones TR, Solano M, Hu H, Téllez-Rojo MM, Peterson KE, Goodrich JM. Trimester-Specific Associations of Prenatal Lead Exposure WITH Infant Cord Blood DNA Methylation at Birth. Epigenetics insights. 2020 Jul;13:2516865720938669. [Link] [PDF]


Other UM-CEHC Publications: 

  • Margaret Banker, Muraly Puttabyatappa, Patrick O’Day, Jaclyn M Goodrich, Angela S Kelley, Steven E Domino, Yolanda R Smith, Dana C Dolinoy, Peter X K Song, Richard J Auchus, Vasantha Padmanabhan, Association of Maternal-Neonatal Steroids with Early Pregnancy Endocrine Disrupting Chemicals and Pregnancy Outcomes, The Journal of Clinical Endocrinology & Metabolism. [Link]

  • Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Hussey Freeland DM, Miller R, Murphy SK. Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group. Environ Health Perspect. 2017;125(4):511-526. [Link]

  • Chen YH, Ferguson KK, Meeker JD, McElrath TF, Mukherjee B. Statistical methods for modeling repeated measures of maternal environmental exposure biomarkers during pregnancy in association with preterm birth. Environ Health. 2015;14:9. [Link]

  • Faulk C, Liu K, Barks, A, Goodrich JM, Dolinoy DC. Longitudinal epigenetic drift in mice perinatally exposed to lead. Epigenetics. 2014;9(7):934-41. [Link]

  • Ferguson KK, McElrath TF, Chen YH, Mukherjee B, Meeker JD. Urinary phthalate metabolites and biomarkers of oxidative stress in pregnant women: a repeated measures analysis. Environmental Health Perspectives. 2015;123(3):210-6. [Link]

  • Ferguson KK, McElrath TF, Cantonwine DE, Mukherjee B, Meeker JD. Phthalate metabolites and bisphenol-A in association with circulating angiogenic biomarkers across pregnancy. Placenta. 2015 Jun;36(6):699-703. [Link]

  • Ferguson KK, Meeker JD, Cantonwine DE, Chen YH, Mukherjee B, McElrath TF. Urinary phthalate metabolite and bisphenol A associations with ultrasound and delivery indices of fetal growth. Environ Int. 2016;94:531-7. [Link]

  • Ferguson KK, Peterson KE, Lee JM, Mercado-Garcia A, Blank-Goldenberg C, Tellez-Rojo MM, Meeker JD. Prenatal and peripubertal phthalates and bisphenol A in relation to sex hormones and puberty in boys. Reprod Toxicol. 2014;47:70-6. [Link]

  • Kochmanski JJ, Marchlewicz EH, Savidge M, Montrose L, Faulk C, Dolinoy DC. Longitudinal effects of perinatal bisphenol A and variable diet exposures on epigenetic drift in mice. Reprod Toxicol. 2016 Aug 2. pii: S0890-6238(16)30308-2. [Link]

  • Lewis RC, Johns LE, Meeker JD. Exploratory analysis of the potential relationship between urinary molybdenum and bone mineral density among adult men and women from NHANES 2007-2010. Chemosphere. 2015;164:677-682. [Link]

  • Lewis RC, Johns LE, Meeker JD. Serum Biomarkers of Exposure to Perfluoroalkyl Substances in Relation to Serum Testosterone and Measures of Thyroid Function among Adults and Adolescents from NHANES 2011-2012. Int J Environ Res Public Health. 2015;12:6098-6114. [Link]

  • Marchlewicz EH, Dolinoy DC, Tang L, Milewski S, Jones TR, Goodrich JM, Soni T, Domino SE, Song PSX, Burant C, Padmanabhan V. Lipid metabolism is a key mediator of developmental epidgenetic programming. Scientific Reports. 2016;6:34857. [Link]

  • Meeker JD, Ferguson KK. Urinary phthalate metabolites are associated with decreased serum testosterone in men, women, and children from NHANES 2011-2012. J Clin Endocrinol Metab. 2014;99(11):4346-52. [Link]

  • Neier K, Marchlewicz EH, Dolinoy DC, Padmanabhan V. Assessing human health risk to endocrine disrupting chemicals: a focus on prenatal exposures and oxidative stress. Endocrine Disruptors. 2015; 3:1, e1069916. [Link]

  • Omoike OE, Lewis RC, Meeker JD. Association between urinary biomarkers of exposure to organophosphate insecticides and serum reproductive hormones in men from NHANES 1999-2002. Reproductive Toxicology. 2015 Jun; 53:99-104. [Link]

  • Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, Padmanabhan V, Taylor HS, Swan SH, VandeVoort CA, Flaws JA. Bisphenol A and Reproductive Health: Update of Experimental and Human Evidence, 2007-2013. Environmental Health Perspectives. 2014;122(8):775-786. [Link]

  • Sanchez-Vaznaugh EV, Sánchez BN, Crawford, PB, Egerter, S. Association between competitive food and beverage policies in elementary schools and childhood overweight/obesity trends: differences by neighborhood socioeconomic resources. JAMA Pediatr. 2015;169(5):e150781. [Link]

  • Trentacosta CJ, Davis-Kean P, Mitchell C, Hyde L, Dolinoy DC. Environmental contaminants and child development. Child Development Perspectives. 2016. [Link]

  • Vandenberg LN, Gerona RR, Kannan K, Taylor JA, van Breemen RB, Dickenson CA, Liao C, Yuan Y, Newbold RR, Padmanabhan V, vom Saal FS, Woodruff TJ. A round robin approach to the analysis of bisphenol a (BPA) in human blood samples. Environmental Health. 2014;13:25. [Link]

  • Veiga-Lopez A, Kannan K, Liao C, Ye W, Domino S, Padmanabhan V. Gender-specific effects on gestational length and birth weight by early pregnancy BPA exposure. Environ Health Perspect. 2015;123(3):210-6. [Link]

  • Veiga-Lopez A, Pennathur S, Kannan K, Patisaul HB, Dolinoy DC, Zeng L, Padmanabhan V. Impact of gestational bisphenol a on oxidative stress and free Fatty acids: human association and interspecies animal testing studies. Endocrinology. 2015;156(3):911-22. [Link]

  • Watkins DJ, Fortenberry GZ, Sanchez BN, Barr DB, Panuwet P, Bellinger D, Schnaas L, Solano-Gonzalez M, Ettinger AS, Hernandez-Avila M, Hu H, Meeker JD, Téllez-Rojo MM. Urinary 3-phenoxybenzoic acid (3-PBA) in pregnant women from Mexico City: Distribution and relationships with child neurodevelopment. Environ Res. 2016;147:307-13. [Link]

  • Watkins DJ, Milewski S, Domino SE, Meeker JD, Padmanabhan V. Maternal phthalate exposure during early pregnancy and at delivery in relation to gestational age and size at birth: a preliminary analysis. Reprod Toxicol. 2016;65:59-66. [Link]

  • Wu J, Wen XW, Faulk C, Boehnke K, Zhang H, Dolinoy DC, Xi C. Perinatal lead exposure alters gut microbiota composition and results in sex-specific bodyweight increases in adult mice. Toxicol Soc. 2016;151(2):324-33. [Link]

  • Goodrich JM, Dolinoy DC. "Environmental Exposures: Impact on the Epigenome," in Epigenetics: Current Research and Emerging Trends. Edited by Brian Chadwick. Caister Academic Press. 2015.

  • Goodrich JM, Dolinoy DC. "Epigenetics and Carcinogenesis," in Comprehensive Toxicology, Third Edition. Edited by McQueen C and Roberts R. Elsevier Ltd, Oxford, UK. 2017.

  • Liu Y, Peterson KE. "Early Toxicant Exposures and Development Of Obesity In Childhood," in Childhood Obesity: Causes, Consequences and Intervention Approaches. Edited by Michael Goran. Taylor & Francis Group, CRC Press. 2016.

  • Marchlewicz EH, Anderson OS, Dolinoy DC. "Early life exposures and the epigenome – interactions between nutrients and the environment," in The Role of Nutrition and Metabolism on Epigenetic Regulation. Edited by Emily Ho and Frederick Domann. Taylor & Francis Group, CRC Press. 2014.

  • Montrose L, Goodrich JM, Dolinoy DC. "ToxicoEpigenetics and Effects on Life Course and Disease Susceptibility," in Translational Toxicology: Defining a new therapeutic discipline with a focus on windows of susceptibility in reproduction and cancer. Wiley. 2017.

  • Nahar MS, Dolinoy DC. "Critical Windows of Vulnerability," in Comprehensive Toxicology, Third Edition. Edited by McQueen C and Dolinoy D. Elsevier Ltd, Oxford, UK. 2017.

  • Silver MK, Meeker JD. "Endocrine disruption of developmental pathways and children's health," in Endocrine Disruption and Human Health. Edited by Darbre PD. Elsevier Ltd, Oxford, UK. 2015.


Available ELEMENT Datasets and R-Packages:

Data Description: The study population includes 250 pregnant women from a subset of the ELEMENT birth cohorts (cohort 2 and 3). The outcome of interest is infant BMI where weight and length were measured longitudinally. The other variables of interest are BPA and phthalates. BPA and 9 phthalates were measured from urine samples of mothers during three trimesters of pregnancy. Nine phthalates include MEHP, MEHHP, MEOHP, MECPP, MBzP, MBP, MiBP, MEP, and MCPP. Other covariates included are: cohort indicator, infant's sex,  breastfed for 6 months (indicator variable), birth weight (kg),  gestational age, mother's age-at-birth, years of education, marital status, number of previous pregnancy, and current/previous smoking. 

Model Description: The Newton growth model incorporates the Newton’s law of motion in the modeling of infant BMI growth. The researchers proposed a statistical dynamic equation based on a semi-parametric stochastic velocity model to account for this information. is referred to as Newton’s growth model (NGM) in the rest of the paper. 

Keywords: Newton Growth Model, BPA, phthalates, maternal, child, BMI

Key Researchers: Peter X.K. Song, Jonggyu Baek, Wei Perng, Karen Peterson 

Relevant Publications:

Baek, J., Zhu, B. and Song, P.X.-K. (2019). "Bayesian analysis of infant's growth dynamics with in utero exposure to environmental toxicants".  Annals of Applied Statistics 13, 297-320.  

Wei Perng, Jonggyu Baek, Christina W. Zhou, Alejandra Cantoral, Maria Martha Tellez-Rojo, Peter X. K. Song & Karen E. Peterson (2018) "Associations of the infancy body mass index peak with anthropometry and cardiometabolic risk in Mexican adolescents", Annals of Human Biology, DOI: 10.1080/03014460.2018.1506048

Related R- packages: NGM: Bayesian Semi-parametric Stochastic Velocity Model with Ornstein-Uhlenbeck process prior.    

Data Description: The objective of this project is to examine effects of toxicant exposures during three sensitive developmental timeframes – the prenatal period (during 1997-2004), early adolescence (8-14 years), and late adolescence (13-19 years) – on adiposity and metabolic risk in adolescence among participants of the Early Life Exposure to ENvironmental Toxicants (ELEMENT) Project, a Mexican birth cohort in Mexico City. We leverage existing data on toxicant exposure during all three timeframes, including bisphenol A (BPA), metals and phthalates, and propose to measure polycyclic aromatic hydrocarbon (PAH) metabolites in archived urine samples from the mothers and children. Additionally, we will carry out genome-wide DNA methylation analysis in peripheral leukocytes at all three timeframes, and untargeted metabolomics analyses in fasting serum during late adolescence to gain insight into molecular pathways linking exposure to each of these toxicants singly and as mixtures to health outcomes during adolescence.

Keywords: DNA, methylation, untargeted, metabolomic. BPA, phthalates, child

Key Researchers: Wei Perng, Jackie Goodrich, Scott Clipper, Julie Vantine, Jennifer Fernandez 

Relevant Publications:

Perng, Wei, Emily C. Hector, Peter XK Song, Martha Maria Tellez Rojo, Sasha Raskind, Maureen Kachman, Alejandra Cantoral, Charles F. Burant, and Karen E. Peterson. "Metabolomic determinants of metabolic risk in Mexican adolescents." Obesity 25, no. 9 (2017): 1594-1602. DOI: 10.1002/oby.21926 


Description: Fused lasso method to cluster and estimate regression coefficients of the same covariate across different data sets when a large number of independent data sets are combined. Package supports Gaussian, binomial, Poisson and Cox PH models.

Key Researchers: Lu Tang, and Peter X.K. Song


Lu Tang, and Peter X.K. Song. Fused Lasso Approach in Regression Coefficients Clustering -
Learning Parameter Heterogeneity in Data Integration. Journal of Machine Learning Research,
17(113):1-23, 2016.

Fei Wang, Lu Wang, and Peter X.K. Song. Fused lasso with the adaptation of parameter ordering
in combining multiple studies with repeated measurements. Biometrics, DOI:10.1111/biom.12496,